Characterization, Large-Scale HSCCC Separation and Neuroprotective Effects of Polyphenols from Leaves.

leaves have been widely used for the treatment of inflammation, diabetes, high blood pressure, and other diseases, due to being rich in polyphenols. The main objective of this work was to largely separate the main polyphenols from leaves using the technique of high-speed counter-current chromatography (HSCCC). The phenolic composition in leaves was first analyzed qualitatively and quantitatively by UPLC-Q-Exactive Orbitrap/MS and UPLC-QqQ/MS, respectively, indicating that quercetin and kaempferol derivatives, phenolic acid and apigenin are the main polyphenols in leaves, with quercetin and kaempferol derivatives predominating.

Bevacizumab for non-small cell lung cancer patients with brain metastasis: A meta-analysis.

This study evaluates the efficacy and safety of bevacizumab (BEV) in the treatment of non-small cell lung cancer (NSCLC) patients with brain metastases (BM) by performing meta-analyses of response and survival indices. Seventeen studies were included. BEV treatment was associated with a lower new BM incidence (hazard ratio: 0.

Effect of tannin addition on chromatic characteristics, sensory qualities and antioxidant activities of red wines.

Tannin addition as an enological practice has been widely used in the winemaking process because of their ability of improving the aroma and sensory characteristics and stabilizing of color of red wine. In this study, hydrolysable, condensed tannins and their mixtures in different ratios were added into two Merlot wines to investigate their effect on the wine overall quality. The contents of 15 phenolic compounds were detected by HPLC-DAD, CIELAB color parameters were measured using a chromatic aberration meter, sensory evaluation was accomplished using the assessment standards established by the American Wine Association, and antioxidant activities were analyzed using DPPH and ABTS radical tests.

A semisynthetic approach for the simultaneous reaction of grape seed polymeric procyanidins with catechin and epicatechin to obtain oligomeric procyanidins in large scale.

Polymeric procyanidins (PPCs) were the major constituents of procyanidins, while they have poor bioactivity. To better utilize PPCs, a semisynthetic approach for converting PPCs to oligomeric procyanidins (OPCs) was proposed. Grape seed PPCs were simultaneously reacted with catechin (C) and epicatechin (EC) under acid condition.

Protective Effect of Grape Seed Procyanidins against H O -Induced Oxidative Stress in PC-12 Neuroblastoma Cells: Structure-Activity Relationships.

Unlabelled: To establish a structure-activity relationship for procyanidins, we verified the cyto-protective effect of 13 grape seed procyanidins, ranging from monomers to trimers against H O -induced oxidative stress in PC-12 neuroblastoma cells. Our study demonstrated some procyanidins were able to significantly protect PC-12 cells from the H O -induced cytotoxicity suggesting they possess neuroprotective effects against oxidative stress. Procyanidins' protective effects against oxidative stress mainly depended on their polymerization degree in addition to their structural features.

An approach for degradation of grape seed and skin proanthocyanidin polymers into oligomers by sulphurous acid.

To develop an efficient method for degradation of grape seed and skin proanthocyanidins polymers into oligomers, an optimized sulphurous acid degradation conditions for grape seed with the temperature of 60 °C, reaction time of 60 min and sample-sulphurous acid ratio of 1:0.2, and for grape skin with the temperature of 40 °C, reaction time of 60 min and sample-sulphurous acid ratio of 1:0.2, were established.

A demonstration of biofiltration for VOC removal in petrochemical industries.

A biotrickling filter demo has been set up in a petrochemical factory in Sinopec Group for about 10 months with a maximum inlet gas flow rate of 3000 m3 h(-1). The purpose of this project is to assess the ability of the biotrickling filter to remove hardly biodegradable VOCs such as benzene, toluene and xylene which are recalcitrant and poorly water soluble and commonly found in petrochemical factories. Light-weight hollow ceramic balls (Φ 5-8 cm) were used as the packing media treated with large amounts of circulating water (2.