Publications by authors named "Zongkai Zhang"
Background: Nonalcoholic fatty liver disease (NAFLD) may contribute to osteoporosis. Berberine is a traditional Chinese medicine and was recently shown to be beneficial in NAFLD. However, little is known about its impact on bone loss induced by NAFLD.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the correlation between cone-beam CT (CBCT) and positioning CT (pCT) measurements of tumor characteristics in locally advanced rectal cancer and explores the possibility of using CBCT as a substitute for pCT.
- It involved 103 patients undergoing treatment, with their imaging data divided into training and validation sets, using a deep learning model to analyze tumor features.
- Results show that while the modified model performed better with pCT images, several extracted features from both imaging methods are highly correlated, highlighting the potential of CBCT in understanding cancer staging and prognosis.
Objective: There is a lack of research evaluating the effect of tumor markers for prognosis in cervical adenocarcinoma. We aimed to develop and validate a preoperative tumor-marker-based model including clinicopathological factors to clarify the prognostic value of endocervical adenocarcinoma.
Methods: A total of 572 patients with cervical adenocarcinoma who were staged at the International Federation of Gynecology and Obstetrics (FIGO) IA-IIA were reviewed retrospectively.
Objectives: No consensus was reached on the efficacy of postoperative radiotherapy (PORT) in locally invasive thymomas because of the rarity of the thymic epithelial and the variations of study results. Therefore, we aimed to explore the efficacy of PORT in locally invasive thymomas using the Surveillance, Epidemiology, and End Results (SEER) database.
Methods: Patients diagnosed with thymomas from 2004 to 2016 were identified using the SEER database.
Objective: To explore the trajectory of clinical symptoms and biomarkers in the last four weeks of life in terminally ill cancer patients.
Study Design: Observational study.
Place And Duration Of Study: Department of Oncology, Shijingshan hospital, Shijingshan Teaching Hospital of Capital Medical University, Beijing, China, between January 2017 and January 2020.
Objective: To examine the effect of primary recurrence patterns on the prognosis of squamous cervical cancer after initial treatment.
Methods: Primary recurrence patterns and prognostic factors were examined in stage IB-IIA cervical cancer patients after initial treatment. Recurrence site (locoregional recurrence and distant metastasis or in-field and out-field recurrence for patients receiving adjuvant radiotherapy) and subtype (nodal and organ recurrence) were examined.
Objective: The objective of this study was to retrospectively explore the clinical implications of simultaneous intensity-modulated radiotherapy (IMRT) boost to the tumor bed in cervical cancer with full-thickness stromal invasion (FTSI).
Patients And Methods: Patients diagnosed with the International Federation of Gynecology and Obstetrics (FIGO) 2009 stage IB and IIA cervical cancer with confirmed FTSI were included. Patients received pelvic IMRT from a dose of 50.
Background: The potential therapeutic benefit of adjuvant radiotherapy for patients with stage I uterine sarcoma has not been clear. In this study, we aimed to develop a risk scoring model to select the subgroup of patients with stage I uterine sarcoma who might benefit from adjuvant radiotherapy.
Methods: Patients with stage I uterine sarcoma from the Surveillance, Epidemiology, and End Results program from 2010 to 2014 were retrospectively included in this analysis.
Thermal energy exchange induces non-uniform temperature distribution on the concrete bridge structures, leading to variation of static and dynamic properties of structural systems. The finite element method can facilitate thermal simulation and predict the structural temperature distribution based on heat flow theories. Previous studies mainly focused on the daytime with sunny weather, and the effects of solar shadow distribution were not fully considered or even ignored.
View Article and Find Full Text PDFBackground: Small cell carcinoma of the esophagus is a rare malignant tumor. We aimed to explore the chemotherapeutic efficacy on the prognosis of patients with small cell carcinoma of the esophagus who received radiotherapy.
Methods: To identify the population of interest, Surveillance, Epidemiology, and End Results data from 1996 to 2016 were chosen.
Article Synopsis
- Scientists studied the timing of radiation therapy after surgery for a type of esophagus cancer called ESCC to see how it affects patient survival.
- They found that waiting more than 48 days after surgery to start radiation therapy helps patients live longer compared to starting it sooner.
- The research also showed that receiving 2 to 4 cycles of chemotherapy before radiation gives the best survival rates, and they created a tool (nomogram) to help predict how well patients might do.
Objective: We aimed to assess the impact of the treatment modality on the outcome of small cell neuroendocrine cervical carcinoma (SCNEC) using the Surveillance Epidemiology and End Results (SEER) database.
Methods: Patients from the SEER program between 1981 and 2014 were identified. Significant factors for cancer-specific survival (CSS) and overall survival (OS) were analyzed using the Kaplan-Meier survival and Cox regression methods.
Objective: To assess the effect of percutaneous endoscopic lumbar discectomy (PELD) combined with epidural injection for prolapsed lumbar disc herniation(PLDH).
Methods: In this prospective randomized controlled study, the clinical data of 126 patients who had undergone a PELD because of a single-level PLDH from March 2014 to June 2015 were analyzed. There were 67 males and 59 females, ranging in age from 17 to 75 years old with an average of(41.