Effect of the initial pH of the culture medium on the nutrient consumption pattern of Bifidobacterium animalis subsp. lactis Bb12 and the improvement of acid resistance by purine and pyrimidine compounds.

Aims: During fermentation, the accumulation of acidic products can induce media acidification, which restrains the growth of Bifidobacterium animalis subsp. lactis Bb12 (Bb12). This study investigated the nutrient consumption patterns of Bb12 under acid stress and effects of specific nutrients on the acid resistance of Bb12.

Changes in nutrient consumption patterns of Lactobacillus fermentum mediated by sodium lactate.

Background: During high-cell-density culture of Lactobacillus fermentum, the optimal pH is often maintained by adding NaOH. During cultivation at controlled pH, L. fermentum experiences osmotic stress due to the continuous accumulation of sodium lactate as a neutralizer product, affecting its survival in subsequent processing.

Fermented soybean foods: A review of their functional components, mechanism of action and factors influencing their health benefits.

After thousands of years of evolution and development, traditional fermented soybean foods, with their unique charm, have gained a stable place in the global market. With the explosive development of modern biological technologies, some traditional fermented soybean foods that possess health-promoting benefits are gradually appearing. Physiologically active substances in fermented soybean foods have received extensive attention in recent decades.

Mechanical Modeling of Tube Bending Considering Elastoplastic Evolution of Tube Cross-Section.

Aluminum alloy tubes are widely used in various industries because of their excellent performance. Up to now, when the tube is bent, the elastoplastic deformation evolution mechanism of the cross-section has not been clear, and no direct analytical proof has been found. In this paper, based on the bilinear material model assumption, a new mechanical model of tube plane bending deformation is constructed.

Ribosome Profiling Reveals Genome-Wide Cellular Translational Regulation in ATCC 53103 under Acid Stress.

During fermentation and food processing, ATCC 53103 can encounter many adverse conditions, and acid stress is one of them. The purpose of the present study was to investigate the influence of acid stress on the global translational and transcriptional regulation of ATCC 53103. Two pH values (pH 6.

Ribosome Profiling and RNA Sequencing Reveal Genome-Wide Cellular Translation and Transcription Regulation Under Osmotic Stress in ATCC 53103.

To determine whether osmotic pressure affects the translation efficiency of , the ribosome profiling assay was performed to analyze the changes in translation efficiency in . ATCC 53103. Under osmotic stress, differentially expressed genes (DEGs) involved in fatty acid biosynthesis and metabolism, ribosome, and purine metabolism pathways were co-regulated with consistent expression direction at translation and transcription levels.

Nutrient consumption patterns of Lactobacillus plantarum and their application in suancai.

The purpose of the present study was to control the fermentation time and nitrite content of suancai prepared with Lactobacillus plantarum. According to analyses of the consumption amount and rate of nutrients, growth-stimulating nutrients, essential nutrients and nutrients accelerating the fermentation process of suancai, Asp, Thr, Glu, Cys, Tyr, Mg, Mn and inosine were selected as additions to suancai prepared with L. plantarum.

Fabrication of silver nanoparticle sponge leather with durable antibacterial property.

Leather product with durable antibacterial property is of great interest both from industry and consumer's point of view. To fabricate such functional leather, gallic acid modified silver nanoparticles (GA@AgNPs) were first in situ synthesized with a core-shell structure and an average size of 15.3nm.

PEGylated chitosan protected silver nanoparticles as water-borne coating for leather with antibacterial property.

Development of eco-labeled and effectively antibacterial coatings for final leather products has been desiderated both by industry and by consumers. Herein, PEGylated chitosan modified silver nanoparticles (PEG-g-CS@AgNPs) were prepared and characterized by UV-vis spectroscopy, transmission electron microscopy and dynamic light scattering. The antimicrobial activity of such silver nanoparticles was investigated against Gram-negative Escherichia coli (E.

Cell membrane-inspired polymeric micelles as carriers for drug delivery.

In cancer therapy, surface engineering of drug delivery systems plays an essential role in their colloidal stability, biocompatibility and prolonged blood circulation. Inspired by the cell membrane consisting of phospholipids and glycolipids, a zwitterionic phosphorylcholine functionalized chitosan oligosaccharide (PC-CSO) was first synthesized to mimic the hydrophilic head groups of those amphipathic lipids. Then hydrophobic stearic acid (SA) similar to lipid fatty acids was grafted onto PC-CSO to form amphiphilic PC-CSO-SA copolymers.

Charge-conversional and pH-sensitive PEGylated polymeric micelles as efficient nanocarriers for drug delivery.

A novel amphiphilic copolymer, poly (ethylene glycol)-graft-polyethyleneimine/amide (PEG-g-PEI/amide), is synthesized by grafting PEG and1,2-cis-Cyclohexanedicarboxylic anhydride onto the PEI. PEGylated polymeric micelles can be assembled from the amphiphilic copolymers with well-defined nano-sizes, and anti-cancer drugs are successfully loaded into micelle core formed by the amide. The amides with neighboring carboxylic acid groups exhibit pH-dependent hydrolysis and can reversibly shield the cationic charge of amine groups on the PEI, giving the micelles a charge-conversion property from negative to positive in acidic tumor tissue environment.