Publications by authors named "Zong-Yuan Ge"

Background: The importance of age on the development of ocular conditions has been reported by numerous studies. Diabetes may have different associations with different stages of ocular conditions, and the duration of diabetes may affect the development of diabetic eye disease. While there is a dose-response relationship between the age at diagnosis of diabetes and the risk of cardiovascular disease and mortality, whether the age at diagnosis of diabetes is associated with incident ocular conditions remains to be explored.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to create a deep learning algorithm for quickly identifying cognitive impairment using various eye images, specifically from a large dataset collected in Beijing.
  • - Researchers trained five different models on images from the Beijing Eye Study 2011, including fundus photographs and OCT images, ultimately finding that a multimodal model combining both image types performed best in detecting cognitive impairment.
  • - The results showed that the multimodal model achieved an impressive area under the curve (AUC) score of 0.820 in internal validation and around 0.786-0.784 in external validations, indicating its reliability across different patient demographics, with no major variations in performance across sexes or ages.
View Article and Find Full Text PDF

Cataract is the leading cause of blindness worldwide. In order to achieve large-scale cataract screening and remarkable performance, several studies have applied artificial intelligence (AI) to cataract detection based on fundus images. However, the fundus images they used are original from normal optical circumstances, which is less impractical due to the existence of poor-quality fundus images for inappropriate optical conditions in actual scenarios.

View Article and Find Full Text PDF

This study aimed to develop an automated computer-based algorithm to estimate axial length and subfoveal choroidal thickness (SFCT) based on color fundus photographs. In the population-based Beijing Eye Study 2011, we took fundus photographs and measured SFCT by optical coherence tomography (OCT) and axial length by optical low-coherence reflectometry. Using 6394 color fundus images taken from 3468 participants, we trained and evaluated a deep-learning-based algorithm for estimation of axial length and SFCT.

View Article and Find Full Text PDF