Publications by authors named "Zong-Qi Wang"

Stomatal movement is critical for water transpiration, gas exchange, and responses to biotic stresses. Abscisic acid (ABA) induces stomatal closure to prevent water loss during drought. We report that Arabidopsis CIPK8 negatively regulates ABA-mediated stomatal closure and drought tolerance.

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Stomata are a key land plant innovation that permit the regulation of gaseous exchanges between the plant interior and the surrounding environment. By opening or closing, stomata regulate transpiration of water though the plant; and these actions are coordinated with acquisition of CO for photosynthesis. Stomatal movement is controlled by various environmental and physiological factors and associates with multiple intracellular activities, among which the dynamic remodeling of vacuoles plays a crucial role.

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Aims: Endoplasmic reticulum (ER) stress has been demonstrated to regulate neuronal death caused by ischemic insults via activation of apoptosis, but it still remains unclear whether ER stress participates in regulation of parthanatos, a new type of programmed cell death characterized by PARP-1 overactivation and intracellular accumulation of PAR polymer.

Methods: we used oxygen-glucose deprivation (OGD) and human SH-SY5Y cells to simulate neuronal damage caused by ischemia.

Results: Oxygen-glucose deprivation induced time-dependent death in SH-SY5Y cells, which was accompanied with upregulation of PARP-1, accumulation of PAR polymer, decline of mitochondrial membrane potentials and nuclear translocation of AIF.

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Article Synopsis
  • Necroptosis is a programmed cell death process that involves specific proteins (RIP1 and RIP3) and is characterized by the excessive production of reactive oxygen species (ROS), though ROS's exact role in this process is not fully understood.* -
  • In this study, shikonin was used to induce necroptosis in glioma cells, leading to an increase in intracellular ROS and upregulating RIP1 and RIP3 levels, suggesting that these proteins play a crucial role in necroptosis.* -
  • The research found that inhibiting RIP1 or RIP3 prevented necroptosis and reduced ROS levels, while manipulating ROS levels—either reducing them or increasing them—had a direct effect on
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Objective: To identify nasal width changes occurring after Le Fort I osteotomy and to compare prospectively the effect of three surgical techniques for controlling postoperative nasal width.

Methods: In the study, 79 patients (22 male and 57 female, mean age 23.2 ± 3.

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