A pure compound from Roxb. protects neurons against hydrogen peroxide-induced neurotoxicity via the activation of Nrf-2.

Oxidative stress plays a pivotal role in several human diseases including Parkinson's disease (PD). , a member of Zingiberaceae, is widely known in Thailand as an alternative medicinal herb for uterine inflammation and estrogenic properties. In this study (3)-1-(3,4-dihydroxyphenyl)-7-phenyl-(6)-6-hepten-3-ol or compound 092 (C-092, or ASPP 092), a pure compound isolated from ethanol extract of , was evaluated for neuroprotective effect on hydrogen peroxide-induced toxicity in SH-SY5Y cells.