Publications by authors named "Zoltan Szabo-Maak"

Article Synopsis
  • Headache after craniotomy is often overlooked, and this study tested whether a single preoperative dose of dexketoprofen (DEX) could help reduce post-surgery headaches compared to a placebo.
  • The research involved 200 patients and measured pain levels using a visual analogue scale during their hospital stay and at 30- and 90-day follow-ups.
  • Results showed that DEX did reduce pain intensity in the first 24 hours after surgery but had no long-term impact on headache severity or overall pain management in the following weeks.
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Background: Residual neuromuscular block is associated with an increased risk of postoperative pulmonary complications in retrospective studies. The aim of our study was to investigate prospectively the incidence of postoperative pulmonary complications after reversal with either sugammadex (SUG) or neostigmine (NEO) in high-risk older patients.

Methods: We randomly allocated 180 older patients with significant morbidity (ASA physical status 3) ≥75 yr old to reversal of rocuronium with either SUG or NEO.

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Background: Certain surgical interventions may require a deep neuromuscular block (NMB). Reversal of such a block before tracheal extubation is challenging. Because anticholinesterases are ineffective in deep block, sugammadex 4 mg/kg has been recommended for the reversal of rocuronium- or vecuronium-induced deep NMB.

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Background: Rocuronium-induced neuromuscular block that spontaneously recovered to a train-of-four count of four can be reversed with sugammadex 0.5 or 1.0 mg/kg.

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Background: Electronic neuromuscular monitoring is not widely used to determine either the reversal requirements for neuromuscular block before extubation of the trachea, or to determine if there is any subsequent postoperative residual neuromuscular block (PORNB).

Objectives: To investigate the incidence of PORNB using acceleromyography after spontaneous recovery of rocuronium-induced block and to compare this with the administration of sugammadex, neostigmine or a placebo.

Design: Partially randomised, partially randomised, placebo-controlled, double-blind, four-group parallel-arm study.

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