A novel fiber-optic based 0.014″ pressure wire: Designs of the OptoWire™, development phases, and the O first-in-man results.

Objectives: To review the technical limitations of available pressure-wires, present the design evolution of a nitinol fiber-optic pressure wire and to summarize the First-in-Man (FIM) O pilot study results.

Background: Despite increasing use of physiology assessment of coronary lesions, several technical limitations persist. We present technical details, design evolution and early clinical results with a novel 0.