Publications by authors named "Zola Stephenson"
Article Synopsis
- Current treatments for dysphagia in ALS fail to address the root causes like tongue weakness and muscle atrophy, prompting a study using the LCN-SOD1 mouse model to explore this issue.
- The study followed 125 LCN-SOD1 offspring to analyze limb strength's impact on dysphagia and survival rates; results showed a high occurrence of swallowing difficulties in mixed phenotype mice compared to hindlimb phenotype mice.
- Findings indicated that both mouse groups had significant tongue muscle atrophy, supporting the potential of this model for developing targeted treatments for dysphagia in ALS.
