Publications by authors named "Zohreh Sadeghi"
Purpose: Intensive chemotherapy with daunorubicin (DNR) is associated with serious side effects in acute myeloid leukemia (AML) patients. In this study the effect of small-molecule BH3-mimetic, ABT-737, on the sensitivity of HL60 and U937 AML cell lines was investigated.
Methods: The cytotoxic effects of DNR and ABT-737, alone or in combination were assessed using MTT assay and combination index analysis.
Article Synopsis
- The study investigates factors that contribute to suboptimal myocardial reperfusion in STEMI patients undergoing primary PCI, finding that while procedural success was high, complete ST resolution was significantly lower.
- Key predictors of failed reperfusion include the time of symptom onset, ejection fraction, and the presence of more than three cardiac risk factors, while demographics and previous heart-related procedures did not show significant associations.
- It is suggested that assessing a patient’s risk profile, particularly timing and heart function, can help predict the likelihood of effective myocardial reperfusion after treatment.
Background: Histology is the unique method for diagnosis of silent liver diseases; so, we aimed to determine the prevalence of fatty liver and other silent liver diseases among those who passed away for causes other than liver diseases in Tehran.
Methods: Over a two-year period (2002 - 2004) we enrolled autopsies performed at the Forensic Medicine Center in Tehran. Demographic information, history of known acute and chronic liver diseases, and causes of death were determined.