Cardiac function in pemphigus vulgaris patients before and after steroid pulse therapy.

Background: Pemphigus vulgaris which is an autoimmune dermatological disorder characterized by vesiculobullous lesions over the skin and mucosae may also give rise to cardiac disease. Global Longitudinal Strain (GLS) measurement may help to predict cardiac dysfunction in these patients.

Method: In this prospective study, the GLS was measured before and after steroid pulse therapy in pemphigus vulgaris patients using 2 D speckle-tracking echocardiography.

Electrocardiographic changes after high-dose corticosteroid pulse therapy in pemphigus patients.

Purpose: The objective of the current study was to evaluate the effect of intravenous methylprednisolone pulse therapy on myocardial repolarization alterations, especially QT dispersion in anticipation of cardiovascular risks in patients with pemphigus vulgaris.

Methods: The current study is a prospective-controlled study on the electrocardiographic changes after methylprednisolone pulse therapy in 50 patients with pemphigus vulgaris.

Results: A total of 50 patients (28 female and 22 male) were included in our study.

Evaluation of the young children with neurodevelopmental disability: a prospective study at hamadan university of medical sciences clinics.

Objective: Developmental impairment is a common problem in children health that occurs in approximately 5-10% of the childhood population. The aim of this study was to determine the etiologic yield of subspecialists' evaluation of young children with developmental disability.

Materials & Methods: All children aged between 2 months and 5 years referred over a 15-month period to Hamadan University of Medical Sciences subspecialty services for initial evaluation of a suspected developmental Disability, were enrolled in the present study.