Publications by authors named "Zohre Ganji"
Article Synopsis
- iRBD (idiopathic REM sleep behavior disorder) may signal the early onset of α-synucleinopathies like Parkinson's disease and dementia with Lewy bodies, but there is a lack of studies on cortical surface morphology.
- This research examined 30 patients with probable iRBD and 33 healthy controls, utilizing MRI and neurophysiological tests to analyze cortical thickness, gyrification, and sulcal depth.
- Results showed that piRBD patients had reduced cortical thickness and volume in several brain regions and found correlations between brain morphology and clinical assessments, suggesting potential early diagnostic markers for iRBD.
Rapid eye movement behavior disorder (RBD) is a parasomnia characterized by the loss of skeletal muscle atonia during the rapid eye movement (REM) sleep phase. On the other hand, idiopathic RDB (iRBD) is considered the prelude of the various α-synucleinopathies, including Parkinson's disease (PD), dementia with Lewy bodies and multiple system atrophy. Consequently, over 40% of patients eventually develop PD.
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