How Latine youth's positive development unfold through farmwork in rural migrant farmworker families in the U.S. Midwest.

Some Latine youth from rural migrant farmworker communities engage in farmwork to help support themselves and their families. Although research has documented their motives for working and some characteristics of their employment, knowledge about how these youth construct their work in the fields and how such experiences relate to their positive development is needed to depict their holistic experiences. Using mixed methods, we explored youth's farmwork experiences and examined how these experiences relate to youth's prosocial behaviors, civic responsibility, and ego-resiliency.

Long-term trajectories of depressive symptoms by military affiliation.

Objectives: Using a national sample of Americans, this study estimated and compared patterns of depressive symptom trajectories stratified by military service. This study then examined associations between sociodemographic factors theorized to shape entry into military service and trajectory patterns.

Method: Data came from the National Longitudinal Study of Adolescent to Adult Health, a nationally representative study that followed participants from adolescence (1994-1995) through midlife (2016-2018).

Caring for Patients Experiencing Incarceration: Development of an Online Learning Resource for Physicians in Training.

Many patients experiencing incarceration (PEI) in the United States (U.S.) have significant and complex medical conditions that require offsite consultation and hospitalization.

Psychosocial Factors, Stress and Sleep Among Rural Appalachian Kentucky Residents with Type 2 Diabetes Mellitus.

Introduction: Rural Appalachian residents experience higher rates of most chronic diseases, including type 2 diabetes mellitus (T2DM). Stress and sleep deficiency also are common in the region.

Purpose: To better understand these associated health burdens, the relationship among these conditions and psychosocial factors-such as depressive symptoms, distress, empowerment, and social support-was examined among Appalachian residents with T2DM.

Military service and sociodemographic determinants of depressive symptom trajectories.

Little is known about preservice depressive symptoms, their linkages to subsequent depressive symptoms, and the role of sociodemographic factors in shaping depressive symptoms of those who serve in the military. Using data from the National Longitudinal Study of Adolescent to Adult Health (n = 18,910), we modeled depressive symptom trajectories from baseline (M = 15.67) through midlife and compared differences in depressive symptoms between participants who did and did not enter military service.

Structural risks and family adjustment in midwestern Latine immigrant families: Extending the family stress model.

Objectives: We tested an extended family stress model of economic hardship (FSM; Conger et al., 2010) incorporating structural risks (discrimination, immigration, and COVID-19 experiences) and qualitative data, to better understand the impact of culturally relevant experiences on family stress processes in rural, immigrant Latine families in the U.S.

Older adults using social support to improve self-care (OASIS): Adaptation, implementation and feasibility of peer support for older adults with T2D in appalachia: A feasibility study protocol.

Introduction: The prevalence of type 2 diabetes (T2D) is 17% higher in rural dwellers compared to their urban counterparts, and it increases with age, with an estimated 25% of older adults (≥ 65 years) diagnosed. Appropriate self-care is necessary for optimal clinical outcomes. Overall, T2D self-care is consistently poor among the general population but is even worse in rural-dwellers and older adults.

Training Among Noncustodial Health Care Workers Caring for Patients Experiencing Incarceration: A Preliminary Investigation.

People experiencing incarceration in the United States receive much of their health care outside of custodial settings. Optimizing care in this setting requires further understanding of the training and experiences of noncustodial health care workers. We conducted a cross-sectional, exploratory survey of health care workers at a single academic institution to assess their training and experiences related to caring for this patient population.

'Welcome to my world': a thematic analysis of the lived experiences of people with Myalgic Encephalomyelitis during the UK COVID-19 lockdown.

Objectives: We explore the experiences of people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (pwME/CFS) during the first UK COVID-19 lockdown period. We specifically probe perceived commonalities and departures in experience between government- and health-imposed lockdowns, application of coping strategies for social isolation, and predictions for inclusion of the chronically ill in post-pandemic society.

Methods And Measures: Thirty semi-structured interviews were conducted in pwME/CFS between June - July, 2020.

Stress and Health Outcomes in Midwestern Latinx Youth: The Moderating Role of Ethnic Pride.

Background: Stress has been linked to numerous health outcomes, including internalizing and externalizing behaviors, self-esteem, and physical health. Culture has also been linked to stress and health. This study examined the links between stress and health, and the potential moderating role of Latinx ethnic pride (LEP).

Perturbations during Gait: A Systematic Review of Methodologies and Outcomes.

Background: Despite extensive literature regarding laboratory-based balance perturbations, there is no up-to-date systematic review of methods. This systematic review aimed to assess current perturbation methods and outcome variables used to report participant biomechanical responses during walking.

Methods: Web of Science, CINAHL, and PubMed online databases were searched, for records from 2015, the last search was on 30th of May 2022.

Long-Term Cognitive Outcomes and Associated Quality of Life of Young Adults Who Experienced Liver Transplantation in Early Childhood.

We evaluated long term outcomes in infants born between 1992 and 2002 with cholestatic liver disease (CLD) who underwent successful liver transplantation (LT). A total of 160 children with CLD were identified: 68 had developmental assessments before and after LT of whom 32 were excluded because they were followed up elsewhere; 16/36 consented to complete measures of IQ, anxiety, depression, health related quality of life (HRQoL), and a habits/employment survey. Illness severity and developmental attainment prior to LT were comparable with the 32 excluded and 20 patients who declined to take part.

Multi-type childhood maltreatment exposure and substance use development from adolescence to early adulthood: A GxE study.

Background: Childhood maltreatment types can co-occur and are associated with increased substance use during adolescence and early adulthood. There is also a strong genetic basis for substance use which interacts with environmental factors (e.g.

Individual factors in the relationship between stress and resilience in mental health psychology practitioners during the COVID-19 pandemic.

Utilising an online survey, this study aimed to investigate the concurrent effects of pre-pandemic and COVID-19 stress on resilience in Mental Health Psychology Practitioners (MHPPs) (  325), focussing on the mediation effects of specific individual factors. Optimism, burnout and secondary traumatic stress, but not coping strategies, self-efficacy, compassion satisfaction, or self-compassion, mediated both the relationship between pre-pandemic stress and resilience and COVID-19 stress and resilience. Increased job demands caused by the pandemic, the nature and duration of COVID-19 stress may explain this finding.

Strengths of the heart: Stressors, gratitude, and mental health in single mothers during the COVID-19 pandemic.

The Coronavirus disease (COVID-19) pandemic has created significant economic, social, and mental health challenges for many parents. However, single mothers (who are typically both primary caregivers and wage earners for their families) may be especially vulnerable to stress and mental health problems during this crisis. Gratitude is strongly linked to positive emotions as well as mental health and has been shown to be amendable in interventions but has rarely been assessed in regard to parent well-being.

An optimized intracerebroventricular injection of CD4 T cells into mice.

The blood-brain barrier acts as a major barrier for the entrance of most therapeutics into the brain, impeding treatment for neurological disorders. Intracerebroventricular (ICV) injection of T cells is a useful tool for cell therapy of neurological disorders including neurodegenerative and neuropsychiatric diseases and brain tumors. Here, we present an optimized ICV injection of T cells with improved injection efficiency at pathological sites within the brain parenchyma.

An optimized protocol for the retroviral transduction of mouse CD4 T cells.

Transduction of primary T cells has become prominent with the introduction of chimeric antigen receptor T-cell therapy. Although there are many protocols for the transduction of human T cells, it remains a challenge to transduce murine T cells. We present an optimized protocol for the retroviral transduction of murine CD4 T cells, which overcomes major challenges including large-scale production and long-term culturing of transduced cells.

The impact of saturated fat, added sugar and their combination on human hippocampal integrity and function: A systematic review and meta-analysis.

Paralleling animal research, there is emerging evidence that a Western-style (WS) diet - high in saturated fat and added sugar - impairs human hippocampal functioning. However, the conditions under which this occurs are not fully understood and there have been published failures to detect such effects. To date, there has been no systematic review or meta-analysis of relevant human studies.

Life-extended glycosylated IL-2 promotes Treg induction and suppression of autoimmunity.

IL-2 is the master-regulator cytokine for T cell dependent responses and is crucial for proliferation and survival of T cells. However, IL-2-based treatments remained marginal, in part due to short half-life. Thus, we aimed to extend IL-2 half-life by flanking the IL-2 core with sequences derived from the extensively glycosylated hinge region of the NCR2 receptor.

The influence of choline treatment on behavioral and neurochemical autistic-like phenotype in Mthfr-deficient mice.

Imbalanced one carbon metabolism and aberrant autophagy is robustly reported in patients with autism. Polymorphism in the gene methylenetetrahydrofolate reductase (Mthfr), encoding for a key enzyme in this pathway is associated with an increased risk for autistic-spectrum-disorders (ASDs). Autistic-like core and associated behaviors have been described, with contribution of both maternal and offspring Mthfr genotype to the different domains of behavior.

Developmental antecedents of adolescent optimism in rural midwestern U.S. Latinx youth.

Aims: Decades of scientific research have found optimism to have wide-ranging effects on individuals' health and well-being. Researchers have largely examined optimism in adults, but have begun addressing the benefits of optimism in adolescents. Challenges and stressors in adolescence can threaten youths' subjective well-being; therefore, identifying factors that contribute to the growth of optimism could have important health implications.

Complexity, symmetry and variability of forward and backward walking at different speeds and transfer effects on forward walking: Implications for neural control.

This study aimed to investigate effects of walking direction and speed on gait complexity, symmetry and variability as indicators of neural control mechanisms, and if a period of backward walking has acute effects on forward walking. Twenty-two young adults attended 2 visits. In each visit participants walked forwards at preferred walking speed (PWS) for 3-minutes (pre) followed by 5-minutes walking each at 80%, 100% and 120% of PWS of either forward or backward walking then a further 3-minutes walking forward at PWS (post).

Associations between Effortful Control, Cortisol Awakening Response, and Depressive Problems in Latino Preadolescents.

The present study examined associations between effortful control, a trait marker of self-regulation, adaptive HPA system functioning (as reflected by the CAR), and concurrent and longitudinal depressive problems, in a sample of preadolescent Latino youth ( = 119, mean age = 11.53 years, 59% female). We hypothesized that trait readiness for self-regulation (e.

Parental restrictive feeding with Latinx adolescents: Examining the role of adolescent effortful control.

The objective of this study was to test if youth effortful control, a general process of self-regulation that is rooted in temperament, uniquely predicts maternal restrictive feeding with Latinx adolescents above and beyond demographic/contextual factors, prior use of restrictive feeding, and common markers of obesity-proneness. The study sample consisted of Latinx fifth and sixth graders and their mothers residing in the Midwestern U.S.

Stabilization of O-O Bonds by d Cations in LiNiWO (0 ≤ x ≤ 0.25) Rock Salt Oxides as the Origin of Large Voltage Hysteresis.

Multinary lithium oxides with the rock salt structure are of technological importance as cathode materials in rechargeable lithium ion batteries. Current state-of-the-art cathodes such as LiNiMnCoO rely on redox cycling of earth-abundant transition-metal cations to provide charge capacity. Recently, the possibility of using the oxide anion as a redox center in Li-rich rock salt oxides has been established as a new paradigm in the design of cathode materials with enhanced capacities (>200 mAh/g).