Sexually dimorphic effects of acute nicotine administration on arousal and visual-spatial ability in non-smoking human volunteers.

The effect of an acute administration of nicotine on arousal and visual-spatial ability in healthy non-smoking participants was investigated. Healthy adult volunteers with a mean age of 19.98 years received a transdermal nicotine or placebo patch prior to completing a water-level task and two mental rotation tasks while concurrent psychophysiological recordings were taken.