Real-World Prevalence, Treatment Patterns, and Outcomes for Patients With HER2 (ERBB2)-Mutant Metastatic Non-Small Cell Lung Cancer, From a US-Based Clinico-Genomic Database.

Objectives: Targeted therapies have been shown to improve outcomes in metastatic non-small cell lung cancer (mNSCLC) with driver mutations. We evaluated the real-world prevalence of human epidermal growth factor receptor 2 (HER2; ERBB2) tumor gene mutations among patients with mNSCLC and described historical treatments and outcomes in patients with HER2-mutant mNSCLC, during a period when there was no approved targeted therapy for HER2-mutant mNSCLC.

Materials And Methods: This retrospective observational study used a US nationwide de-identified NSCLC clinico-genomic database.

Breaking the traditional: a survey of algorithmic mechanism design applied to economic and complex environments.

The mechanism design theory can be applied not only in the economy but also in many fields, such as politics and military affairs, which has important practical and strategic significance for countries in the period of system innovation and transformation. As Nobel Laureate Paul said, the complexity of the real economy makes it difficult for "Unorganized Markets" to ensure supply-demand balance and the efficient allocation of resources. When traditional economic theory cannot explain and calculate the complex scenes of reality, we require a high-performance computing solution based on traditional theory to evaluate the mechanisms, meanwhile, get better social welfare.

Improved polar-code-based efficient post-processing algorithm for quantum key distribution.

Combined with one-time pad encryption scheme, quantum key distribution guarantees the unconditional security of communication in theory. However, error correction and privacy amplification in the post-processing phase of quantum key distribution result in high time delay, which limits the final secret key generation rate and the practicability of quantum key distribution systems. To alleviate this limitation, this paper proposes an efficient post-processing algorithm based on polar codes for quantum key distribution.

Real-time visible light positioning supporting fast moving speed.

Real-time capability is a key factor which affects the practicality of an indoor positioning system significantly. While visible light positioning (VLP) is widely studied since it can provide indoor positioning functionality with LED illumination, the existing VLP systems still suffer from the high positioning latency and are not practical for mobile units with high moving speed. In this paper, a real-time VLP system with low positioning latency and high positioning accuracy is proposed.