J Child Adolesc Psychopharmacol
August 2010
Objective: The aim of this study was to conduct a pilot study testing whether single-dose, immediate-release dexmethylphenidate (dMPH) can facilitate tic suppression in children and adolescents with attention-deficit/hyperactivity disorder (ADHD) and Tourette's disorder (TD) or chronic tic disorders. The primary hypothesis is that dMPH will improve behaviorally reinforced tic suppression in a standard tic suppression paradigm (TSP).
Methods: Ten children with ADHD and TD were given dMPH on one visit and no medication on another, using a random crossover design.