Pulmonary artery pressure changes in primary pulmonary hypertension after verapamil and oxygen.

A comparison of verapamil (V) and oxygen (O) effect on pulmonary artery pressures (PAP) was carried out in 7 patients with primary pulmonary hypertension (PPH). The changes of PAP were examined, first, after O breathing, then after 10 mg of V infused into the pulmonary artery and, finally, after a second oxygen test repeated at the peak of V action. A 15% decrease in PA systolic and diastolic pressures and total pulmonary resistance after V was used as the criterion of a positive effect.

Influence of a single dose of captopril on pulmonary haemodynamics and right ventricular function in mitral stenosis with pulmonary hypertension.

The response of the pulmonary circulation to captopril 75 mg has been examined in 21 patients with pulmonary hypertension secondary to mitral stenosis. The effects of captopril were measured every 15 min up to 2 h by recording pressures in the pulmonary and systemic circulations and by measuring cardiac output. Pulmonary artery systolic pressure fell significantly by 21.

Coronary circulation and myocardial metabolism in dilated cardiomyopathy.

Chest pain is a frequent complaint in patients with dilated cardiomyopathy (DCMP). Myocardial blood flow, coronary circulation parameters and coronary sinus lactate content were measured in 14 patients with DCMP and 10 healthy subjects. Myocardial blood flow in DCMP was 53.