Giant Polarizability and Origin of Ferroelectricity in Layered Materials with a Litharge-Type Structural Unit.

We discover that a large family of [PbF]- and [BiO]-based mixed-anion materials with a litharge-type structural unit are highly polarizable layered semiconductors in proximity to strain-induced ferroelectricity. First-principles calculations demonstrate that in this family of materials, compounds as diverse as PbFBr, BiOCl, BiCuOSe, BiOS, and BiOSCl exhibit static dielectric constants an order of magnitude higher than typical semiconductors. Additionally, they undergo a ferroelectric transition when subjected to a few percent of tensile strain.

Enhancing biomedical named entity recognition with parallel boundary detection and category classification.

Background: Named entity recognition is a fundamental task in natural language processing. Recognizing entities in biomedical text, known as the BioNER, is particularly crucial for cutting-edge applications. However, BioNER poses greater challenges compared to traditional NER due to (1) nested structures and (2) category correlations inherent in biomedical entities.

Scalable Synthesis of 2D ErOCl with Sub-meV Narrow Emissions at Telecom Band.

Van der Waals (vdWs) materials are promising candidates for hetero-integration with silicon photonics toward miniaturization and integration. VdWs materials like molybdenum telluride and black phosphorus, despite being prominent, exhibit air sensitivity, and their room temperature emissions can be significantly broadened by tens of meV. Here, a self-encapsulation strategy is developed to scalably synthesize robust 2D vdWs ErOCl with sub-meV narrow emissions at the telecom C-band.

Phase Engineering of Giant Second Harmonic Generation in BiOSe.

2D materials with remarkable second-harmonic generation (SHG) hold promise for future on-chip nonlinear optics. Relevant materials with both giant SHG response and environmental stability are long-sought targets. Here, the enormous SHG from the phase engineering of a high-performance semiconductor, BiOSe (BOS), under uniaxial strain, is demonstrated.

Intrinsic negative Poisson's ratio of the monolayer semiconductor-TeO2.

Monolayer semiconductors with unique mechanical responses are promising candidates for novel electromechanical applications. Here, through first-principles calculations, we discover that the monolayer-TeO2, a high-mobility-type and environmentally stable 2D semiconductor, exhibits an unusual out-of-plane negative Poisson's ratio (NPR) when a uniaxial strain is applied along the zigzag direction. The NPR originates from the unique six-sublayer puckered structure and hinge-like Te-O bonds in the 2D-TeO2.

Predictive value of frailty assessment tools in patients undergoing surgery for gastrointestinal cancer: An observational cohort study.

Background: Few studies have simultaneously compared the predictive value of various frailty assessment tools for outcome measures in patients undergoing gastrointestinal cancer surgery. Therefore, it is difficult to determine which assessment tool is most relevant to the prognosis of this population.

Aim: To investigate the predictive value of three frailty assessment tools for patient prognosis in patients undergoing gastrointestinal cancer surgery.

Lone-pair-induced formation of intrinsic one-dimensional SbSX (X = Cl, Br, I) helix chain materials.

Intrinsic one-dimensional (1D) helix chain materials are extremely rare in inorganic chemistry due to their novel structural features and complex syntheses. Herein, we report a class of inborn 1D helix chains, namely 1D SbSX (X = Cl, Br, I), that can exist stably. Through calculations, we demonstrate that the formation of this helical feature is facilitated by the lone pairs in antimony atoms.

Fabrication of magnetic-FeO/FeOheterostructure nanorods via the urea hydrolysis-calcination process and their biocompatibility with LOand HepGcells.

-FeOOH nanorods were prepared via the urea hydrolysis process with the average length of 289.1 nm and average diameter of 61.2 nm, while magnetic-FeO/FeOheterostructure nanorods were prepared via the urea calcination process with-FeOOH nanorods as precursor, and the optimum conditions were the calcination temperature of 400 °C, the calcination time of 2 h, the-FeOOH/urea mass ratio of 1:6.

Electrochemical peptide nucleic acid functionalized α-FeO/FeO nanosheets for detection of CYP2C19*2 gene.

The CYP2C19*2 gene carriers and non-carriers are closely related to the dosage of clopidogrel. To correctly guide the use of clopidogrel and promote individualized therapy, an ultra-sensitive electrochemical biosensor was developed for the detection of CYP2C19*2 gene. The heterogeneous α-FeO/FeO nanosheets were prepared via the hydrothermal-calcination process, and the preparation parameters were optimized.

Achieving Ferroelectricity in a Centrosymmetric High-Performance Semiconductor by Strain Engineering.

Phase engineering by strain in 2D semiconductors is of great importance for a variety of applications. Here, a study of the strain-induced ferroelectric (FE) transition in bismuth oxyselenide (Bi O Se) films, a high-performance (HP) semiconductor for next-generation electronics, is presented. Bi O Se is not FE at ambient pressure.

Effect and mechanism of paclitaxel loaded on magnetic FeO@mSiO-NH-FA nanocomposites to MCF-7 cells.

Magnetic FeO nanoparticles were prepared via a simple hydrothermal method and utilized to load paclitaxel. The average particle size of FeO nanoparticles was found to be 20.2 ± 3.

Label-free electrochemical aptasensor based on magnetic α-FeO/FeO heterogeneous hollow nanorods for the detection of cancer antigen 125.

A label-free electrochemical aptasensor based on magnetic α-FeO/FeO heterogeneous hollow nanorods was developed for the detection of cancer antigen 125 (CA125). Magnetic α-FeO/FeO heterogeneous hollow nanorods were successfully prepared by the hydrolysis-calcination method, functionalized with polyethyleneimine (PEI), and modified with HAuCl to form magnetic α-FeO/FeO-Au nanocomposites with a layer of 5 nm gold nanoparticles (Au NPs) on the surface. The magnetic α-FeO/FeO-Au nanocomposites were used to fix the DNA-aptamer probe to amplify the current signal.

Construction of targeted delivery system for curcumin loaded on magnetic α-FeO/FeO heterogeneous nanotubes and its apoptosis mechanism on MCF-7 cell.

In this work, the magnetic α-FeO/FeO heterogeneous nanotubes were successfully prepared by solvent hydrothermal-controlled calcination method. The effects of additive concentration, hydrothermal temperature and time on morphology of products were investigated. The α-FeO/FeO nanotubes with a saturation magnetization of 50 emu/g were prepared calcinated at 600 °C for 4 h using 0.

Giant Modulation of the Electron Mobility in Semiconductor BiOSe via Incipient Ferroelectric Phase Transition.

High-mobility layered semiconductors have the potential to enable the next-generation electronics and computing. This paper demonstrates that the ultrahigh electron mobility observed in the layered semiconductor BiOSe originates from an incipient ferroelectric transition that endows the material with a robust protection against mobility degradation by Coulomb scattering. Based on first-principles calculations of electron-phonon interaction and ionized impurity scattering, it is shown that the electron mobility of BiOSe can reach 10 to 10 cm V s over a wide range of realistic doping concentrations.

Spatially Confined Synthesis of SnSe Spheres Encapsulated in N, Se Dual-Doped Carbon Networks toward Fast and Durable Sodium Storage.

On account of the high theoretical capacity and preferable electrochemical reversibility, tin selenides have emerged as potential anode materials in the field of sodium ion batteries (SIBs). Unfortunately, the large volume changes, low electrical conductivity, and shuttling effect of polyselenides have impeded their real application. In this work, we present a spatially confined reaction approach for controllable fabrication of SnSe spheres, which are embedded in polydopamine (PDA)-derived N, Se dual-doped carbon networks (SnSe@NSC) through a one-step carbonization and selenization method.

Jiangzhi Granule attenuates non-alcoholic steatohepatitis by suppressing TNF/NFκB signaling pathway-a study based on network pharmacology.

Jiangzhi Granule is a commonly used traditional Chinese medicine for treating non-alcoholic fatty liver disease. However, its key ingredients and underlying mechanisms for attenuating nonalcoholic steatohepatitis (NASH) remain unclear. To address this issue, UPLC-TOF-MS based chemical profiling, network pharmacology and animal experimental validation were employed.

Quantitative Profiling of Oxylipin Reveals the Mechanism of Pien-Tze-Huang on Alcoholic Liver Disease.

Alcoholic liver disease (ALD) is a liver disease caused by long-term alcohol consumption. ROS-mediated oxidative stress is the leading cause of ALD. Pien-Tze-Huang (PZH), a traditional formula, is famous in China.

[Characteristics of clinical effectiveness of bloodletting and proposed ways of mechanism research].

According to the operative characteristics, the stimulated site and the curative effect-emerged site of bloodletting therapy, its clinical characteristics may be divided into three categories: a) local stimulation induced focus-local effect, b) local stimulation induced effect of the distal target organ (point-to-point distal effect), and c) special point stimulation induced broader effect of the whole body. Accordingly, the underlying mechanisms of clinical outcomes mainly involve the improvement of the local microcirculation and secondary changes of inflammatory substances for the first category (local focus). The point-to-point distal effect might mainly involve the innervation of nerve segments, while the broad effect of specific acupoint stimulation might involve multiple levels of the neuro-endocrine-immune system.