Publications by authors named "Ziyang Zhang"

The growing threat of bacterial resistance is a critical global health concern, necessitating the development of more efficient methods for evaluating antimicrobial efficacy. Here, we introduce a technique based on the sensitivity of bacterial collective motion to environmental changes, using motion trajectory analysis for swift antibiotic susceptibility appraisal within a simple spread-out of bacterial droplet. By single cell tracking in bacterial fluids near the droplet edge or boundary-detection of the colony expansion, we achieved rapid evaluation of antibiotic efficacy in under 60 min.

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DLG3, also known as Synapse-associated protein 102 (SAP102), is essential for the organization and plasticity of excitatory synapses within the central nervous system (CNS). It plays a critical role in clustering and moving key components necessary for learning and memory processes. Mutations in the DLG3 gene, which result in truncated SAP102 proteins, have been associated with a range of neurological disorders, including X-linked intellectual disability (XLID), autism spectrum disorders (ASD), and schizophrenia, all of which can disrupt synaptic structure and cognitive functions.

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Lipase can mediate the chemo-enzymatic epoxidation of alkenes with the presence of free carboxylic acid and hydrogen peroxide. Four novel lipases with the abilities of chemo-enzymatic epoxidation were mined from the gene database. Lipase TiL originated from Tilletia indica was identified with significant activity on formation of methyl epoxystearate from methyl oleate.

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For settling the recycling problem of waste polyurethane sponges (PU) and environment pollution of oil spills simultaneously, this work exploited the multifunctional superhydrophobic PU materials via the dip-coating method, which were prepared by anchoring modified FeO and expandable graphite (EG) on PU sponges under the adhesion effect of polydimethylsiloxane (PDMS). The water contact angle and sliding angle of as-prepared PU sponges reached 154.1 ± 1.

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Article Synopsis
  • Optical sensors using fiber Bragg gratings (FBGs) offer resistance to electromagnetic interference and perform well in harsh conditions, but the high cost and complexity of their interrogation systems limit their use.
  • A new method employs a waveguide spectral lens (WSL) and a standard CMOS camera to effectively interrogate FBG sensors without the need for complex optics, demonstrating similar wavelength-temperature sensitivity to commercial systems.
  • The system achieves a temperature resolution of 0.1 °C through deep neural network training, indicating that this approach could lead to affordable and compact FBG interrogation solutions.
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Background And Aims: Data are limited on whether several easily measured indices serve as effective tools for Cardiovascular disease (CVD) risk assessment in hypertensive patients. This study aimed to assess the associations of metabolic score for insulin resistance (METS-IR), lipid accumulation product (LAP), and visceral adiposity index (VAI) with CVD risk in hypertensive patients.

Methods And Results: Our data were drawn from the medical records of primary-care institutions in China.

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  • This study investigates the effectiveness of transcutaneous electrical acupoint stimulation (TEAS) as a complementary therapy for patients with chronic coronary syndromes (CCSs) and aims to determine if it can reduce angina severity.
  • It involves 90 participants split into three groups over a 28-week cycle, with one group receiving TEAS treatment and the others receiving either sham TEAS or no additional treatment, while all groups get basic care.
  • The study has been ethically approved and will share its findings through peer-reviewed publications, with the primary outcome being the 6-minute walk test.
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  • Recovering clear images from motion-blurred photos is hard, and existing methods are limited to a fixed number of frames after training.
  • This study introduces a new framework that uses event camera technology to recover sharp frames at any time interval.
  • The proposed method, which incorporates using a bi-directional recurrent network to process events and blurry image features, shows improved performance in generating sharp sequences compared to current techniques.
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  • Managing weight is crucial for people with hypertension, as weight changes can impact their risk of cardiovascular diseases (CVD), stroke, and heart attacks (myocardial infarction).
  • A study of over 221,000 individuals showed that significant weight loss (≥10%) and weight gain (especially >10%) are linked to higher risks of CVD and other serious health issues.
  • The findings emphasize the need for ongoing weight management and monitoring in hypertensive patients to reduce the likelihood of adverse cardiovascular outcomes.
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  • - The study focuses on improving blurry image deblurring by using event cameras, which are bio-inspired visual sensors, to recover sharp frames from blurry images.
  • - It critiques existing methods that overlook the importance of blur modeling and proposes a new approach that uses an event-assisted blurriness encoder to implicitly model blur in images.
  • - The method integrates blurriness information into a base image unfolding network using novel modulation and aggregation techniques, demonstrating superior performance in experiments compared to current state-of-the-art methods on various datasets.
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Astrophotonics aims to transfer photonic technology to the development of compact astronomical instruments. However, light coupling from a multimode fiber, typically adopted in modern observatories, to a single-mode photonic device still poses a challenge. Though a photonic lantern can enable this transition in a low-loss way, it requires that the number of single-mode fibers (SMFs) at the output is the same as the number of guided modes in the multimode fiber, resulting in a cumbersome fan-out of many single-mode devices to be connected.

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  • The ERMES complex is essential for various cellular functions but its role in filamentous fungi, particularly in relation to DON biosynthesis in Fusarium graminearum, is not well understood.
  • This study found that mutations in the ERMES complex led to changes in mitochondrial structure, decreased ATP and ergosterol production, and defective toxisome formation, which significantly reduced DON biosynthesis.
  • The findings indicate that the ERMES complex is crucial for maintaining mitochondrial morphology, regulating DON production, and influencing the virulence of F. graminearum towards host plants.
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Achieving precise real-time localization and ensuring robustness are critical challenges in multi-user mobile AR applications. Leveraging collaborative information to augment tracking accuracy on lightweight devices and fortify overall system robustness emerges as a crucial necessity. In this paper, we propose a robust centralized collaborative rnulti-agent VI-SLAM system for mobile AR interaction and server-side efficient consistent mapping.

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Biochar has been proved as a promising and efficient filler in bioretention facilities for enhancing the stormwater pollutants removal. However, the migration behaviors of stormwater pollutants in biochar filled bioretention facilities is unclear. In this study, as one of the most typical stormwater pollutants, naphthalene was selected as an example and a HYDRUS-1D model was first used to understand the migration behavior of naphthalene in a bioretention facility.

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S-scheme heterojunction photocatalyst-coupled plasma-resonance effect can enhance the response range and absorption of light and charge transfer, and, at the same time, obtain strong redox ability, which is an effective way to improve CO conversion. In this work, plasma S-scheme heterojunctions of Pd/BiOBr/CdS with heterogeneous interfaces have been successfully constructed by a simple hydrothermal method. The possible reaction mechanism was proposed by in situ infrared, ultraviolet-visible spectroscopy (UV-vis), electron paramagnetic resonance (ESR), density functional theory (DFT), and electrochemical techniques.

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Background: Evidence on the association between handgrip strength (HGS) and health care utilisation among Chinese older adults is scarce. In this study, we aimed to investigate the association of HGS with health care utilisation and to identify whether these associations varied by gender.

Methods: The analytic sample of this prospective cohort study included 6007 Chinese older adults (≥60 years) from 2011 to 2018 waves of the China Health and Retirement Longitudinal Study.

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Background: Diabetic retinopathy (DR) is one of the serious complications of diabetes mellitus (DM). Many studies have identified the risk factors associated with DR, but there is not much evidence on the importance of these factors for DR. This study aimed to investigate the associated factors for patients with type 2 DM (T2DM) and calculate the importance of the identified factors.

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Acute respiratory distress syndrome (ARDS) is a life-threatening condition characterized by severe inflammation and pulmonary dysfunction. Despite advancements in critical care, effective pharmacological interventions for ARDS remain elusive. While Janus kinase 2 (JAK2) inhibitors have emerged as an innovative treatment for numerous autoinflammatory diseases, their therapeutic potential in ARDS remains unexplored.

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Nano-bubble water (NBW) was applied to anaerobic digestion (AD) to alleviate volatile fatty acids (VFAs) inhibition, improve the buffering capacity and CH production in this work. Results indicated that NBW accelerated the consumption of VFAs and prevented inhibition due to VFAs accumulation. Additionally, NBW facilitated a rapid increase in partial alkalinity (PA) and total alkalinity (TA) as well as a corresponding rapid decrease in intermediate alkalinity (IA)/PA and VFA/TA, thereby improving buffering capacity and alleviating VFAs inhibition.

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Background: With orthopedic surgery increasing year on year, the main challenges in bone drilling are thermal damage, mechanical damage, and drill skid. The need for new orthopedic drills that improve the quality of surgery is becoming more and more urgent.

Methods: Here, we report the skidding mechanism of drills at a wide range of inclination angle and propose two crescent drills (CDTI and CDTII).

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Article Synopsis
  • Researchers in AI are currently focused on creating larger and deeper neural networks, referred to as the "big model with external complexity" approach.
  • The text argues for a different approach called "small model with internal complexity," which aims to enhance neuron properties for more efficient AI models.
  • An example provided is the Hodgkin-Huxley (HH) network, which shows that a network with complex internal structures can perform similarly to a larger and simpler network like the leaky integrate-and-fire (LIF) model.
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  • A study looked at how family doctor teams in China work and how they can do better in helping people's health.
  • They collected data from 88 family physician teams in different cities to understand how well they were performing their tasks.
  • The study found that when the connections (density) and structure (centralization) among team members are strong, it helps the team to take better care of patients with chronic diseases.
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Factories play a crucial role in economic and social development. However, fire disasters in factories greatly threaten both human lives and properties. Previous studies about fire detection using deep learning mostly focused on wildfire detection and ignored the fires that happened in factories.

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The mass mortality of Pacific oyster Crassostrea gigas has become a severe ecological and economic concern to Chinese aquaculture, which is proposed to be linked to the phytoplankton community in the farming waters. In the present study, both field and laboratory experiments were conducted to identify the phytoplankton taxa associated with oyster mortality and explore the molecular mechanism by which they affect the physiological health of oysters. The field experiment showed that more serious mortality of oysters was observed in the North Yellow Sea from July to September in 2018 (average survival rate of 75.

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