Improvement of Urolithin A Yield by In Vitro Cofermentation of FUA329 with Human Gut Microbiota from Different Urolithin Metabotypes.

FUA329 converts ellagic acid (EA) to urolithin A (Uro-A), which is not autonomously converted by the gut microbiota to produce highly bioavailable and multibiologically active Uro-A in urolithin metabotype 0 (UM-0) populations. We consider that FUA329 has the potential to be developed as a probiotic. Therefore, we utilized FUA329 for in vitro cofermentation with gut microbiota.