The evaluation value of F-AV-133 PET/CT imaging in the Parkinson's disease crab-eating monkey model.

Objective: To investigate the diagnostic value of fluorine-18-9-fluoropropyl-(+)-dihydrotetrabenazine (F-AV-133) positron emission tomography/computed tomography (PET/CT) for Parkinson's disease (PD) and the metabolic parameter changes in the PD macaque model.

Subjects And Methods: Sixty three macaques were divided into an experimental group (n=55) and a normal group (n=8) for F-AV-133 PET/CT imaging. In the experimental group, the macaques were injected with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) solution into one side of the neck artery 2-3 months before imaging to induce unilateral striatal damage for self-control, while the normal group received no special treatment.

Predictive value of metabolism and its heterogeneity parameters measured by preoperative F-FDG PET/CT for mediastinal occult lymph node metastasis in cN0 lung invasive adenocarcinoma.

Objective: To explore the potential of intratumoral metabolism and its heterogeneous parameters, as measured by preoperative fluorine-18-fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) imaging, to predict mediastinal occult lymph node metastasis in cN0 lung invasive adenocarcinoma.

Subjects And Methods: Seventy five patients were consecutively enrolled from January 2018 to December 2022. All patients underwent F-FDG PET/CT scans within two weeks before surgery, and had mediastinal lymph node metastasis confirmed by pathologic diagnosis after surgery.

Global, regional and national burden of Glaucoma: an update analysis from the Global Burden of Disease Study 2019.

Purpose: As the epidemiological and burden trends of glaucoma are changing, it is extremely necessary to re-investigate geographical differences and trends. Here we use data from the 2019 Global burden of Disease, which aims to report the prevalence and disability-adjusted life years of glaucoma injury to assess the latest epidemiological models and trends from 1990 to 2019.

Method: Annual case numbers, age-standardized rates of prevalence, DALYs, and their estimated annual percentage changes (EAPCs) for glaucoma between 1990 and 2019 were derived from the GBD 2019 study.

Highly Processable Covalent Organic Framework Gel Electrolyte Enabled by Side-Chain Engineering for Lithium-Ion Batteries.

Although covalent organic frameworks (COFs) with a graphene-like structure present unique chemical and physical properties, they are essentially insoluble and infusible crystalline powders with poor processability, hindering their further practical applications. How to improve the processability of COF materials is a major challenge in this field. In this contribution, we proposed a general side-chain engineering strategy to construct a gel-state COF with high processability.

Encapsulating NHBr in a metal organic framework: achieving remarkable proton conduction in a wide relative humidity range.

Proton-conducting materials are key components for constructing high-energy-density electronic devices. In this work, by accumulating NHBr into the nanospace of the classical metal organic framework MIL-101-Cr, a proton conductivity as high as 1.53 × 10 S cm was achieved at 363 K and 100% RH.

Host-Guest Assembly of H-Bonding Networks in Covalent Organic Frameworks for Ultrafast and Anhydrous Proton Transfer.

An anhydrous proton conductor represents a key material for the manufacture of high-energy electrical devices. Incorporation of proton carriers into the vacancies of the porous solid provides an effective method for their preparation, but the weak or even no interactions between the ion carriers and the porous solids causing a serious leaking of ion carriers result in trade-off of long-term conductivity. In this term, we developed a host-guest supramolecular chemistry-induced strategy to assemble hydrogen bond networks along the 1D nanochannels of covalent organic frameworks (COFs) for ultrafast and anhydrous proton transfer (1.

Conjugated Microporous Polymer with C≡C and C-F Bonds: Achieving Remarkable Stability and Super Anhydrous Proton Conductivity.

Introducing nonvolatile liquid acids into porous solids is a promising solution to construct anhydrous proton-conducting electrolytes, but due to weak coordination or covalent bonds building these solids, they often suffer from structural instability in acidic environments. Herein, we report a series of steady conjugated microporous polymers (CMPs) linked by robust alkynyl bonds and functionalized with perfluoroalkyl groups and incorporate them with phosphoric acid. The resulting composite electrolyte exhibits high anhydrous proton conductivity at 30-120 °C (up to 4.