Artificial Intelligence in Physical Therapy: Evaluating ChatGPT's Role in Clinical Decision Support for Musculoskeletal Care.

Background: The integration of artificial intelligence into medicine has attracted increasing attention in recent years. ChatGPT has emerged as a promising tool for delivering evidence-based recommendations in various clinical domains. However, the application of ChatGPT to physical therapy for musculoskeletal conditions has yet to be investigated.

Exploring the molecular mechanisms by which secretory phospholipase a2 regulates lymphatic endothelial cell dysfunction by activating macrophages.

This study offers new insights into the dual role of secretory phospholipase A2 (sPLA2) in lymphedema, highlighting its impact on lymphatic endothelial cell (LEC) functionality. Through transcriptomic analyses and co-culture experiments, we observed that sPLA2 has both protective and detrimental effects on human LECs (HLECs), mediated by macrophage activation. Our findings reveal that while low levels of sPLA2 promote LEC health, excessive sPLA2 leads to dysfunction, emphasizing the significance of the sPLA2/PLA2R axis and arachidonic acid metabolism (AA) in lymphedema pathology.

Pelvic floor rehabilitation in cancer survivorship: an umbrella review.

Purpose: This umbrella review aimed to identify, critically appraise, and summarize current systematic reviews with meta-analyses on the role of pelvic floor rehabilitation in cancer survivorship.

Methods: Four bibliographic databases were searched from inception to August 1, 2024. Two independent reviewers screened the titles and abstracts of 379 records and retrieved 24 full-text systematic reviews.

Transcriptomic and Hormonal Changes in Wheat Roots Enhance Growth under Moderate Soil Drying.

Understanding the mechanisms that regulate plant root growth under soil drying is an important challenge in root biology. We observed that moderate soil drying promotes wheat root growth. To understand whether metabolic and hormonic changes are involved in this regulation, we performed transcriptome sequencing on wheat roots under well-watered and moderate soil drying conditions.

Virtual reality-based supportive care interventions for patients with cancer: an umbrella review of systematic reviews and meta-analyses.

Purpose: This umbrella review aimed to identify, critically appraise, and synthesize current evidence from systematic reviews and meta-analyses on the applications of virtual reality-based supportive care interventions in cancer.

Methods: Three bibliographic databases were searched from inception to February 1, 2024. Two independent reviewers screened the titles and abstracts of 421 records and retrieved 26 full-text systematic reviews.

Effects of virtual reality on balance in people with diabetes: a systematic review and meta-analysis.

Purpose: This systematic review aims to identify, critically appraise, and synthesize the effects of virtual reality on balance in people with diabetes.

Methods: Five biomedical databases were searched from inception to December 15, 2023. Clinical trials investigating the effects of virtual reality on performance-based or patient-reported outcome measures related to balance function among people with diabetes were included.

A gender recognition method based on EEG microstates.

Background: Gender carries important information related to male and female characteristics, and a large number of studies have attempted to use physiological measurement methods for gender classification. Although previous studies have shown that there exist statistical differences in some Electroencephalographic (EEG) microstate parameters between males and females, it is still unknown that whether these microstate parameters can be used as potential biomarkers for gender classification based on machine learning.

Methods: We used two independent resting-state EEG datasets: the first dataset included 74 females and matched 74 males, and the second one included 42 males and matched 42 females.

Amyloplast is involved in the MIZ1-modulated root hydrotropism.

Roots exhibit hydrotropism in response to moisture gradients, with the hydrotropism-related gene Mizu-kussei1 (MIZ1) playing a role in regulating root hydrotropism in an oblique orientation. However, the mechanisms underlying MIZ1-regulated root hydrotropism are not well understood. In this study, we employed obliquely oriented experimental systems to investigate root hydrotropism in Arabidopsis.

Pelvic floor muscle training in telerehabilitation: a systematic review and meta-analysis.

Purpose: This systematic review aims to identify, critically appraise, and summarize current evidence regarding the feasibility and efficacy of pelvic floor muscle training in telerehabilitation.

Methods: Three bibliographic databases, PubMed, Embase, and Scopus were searched from inception to October 1, 2023. Clinical trials assessing the feasibility and efficacy of pelvic floor muscle training in telerehabilitation were eligible for inclusion.

Performance-based outcome measures of upper extremity in virtual reality and telerehabilitation: a systematic review.

Objectives: This systematic review aimed to identify and synthesize evidence regarding measurement properties of upper extremity performance-based outcome measures performed in virtual reality or in telerehabilitation to inform clinical applications and research endeavors.

Methods: Five bibliographic databases, PubMed, Embase, CINAHL, APA PsycINFO, and Scopus, were searched on July 12, 2023. Studies assessing the measurement properties (reliability, validity, responsiveness) of upper extremity performance-based outcome measures in virtual reality and telerehabilitation were eligible for inclusion.

HEMORRHAGIC SHOCK ASSESSED BY TISSUE MICROCIRCULATORY MONITORING: A NARRATIVE REVIEW.

Hemorrhagic shock (HS) is a common complication after traumatic injury. Early identification of HS can reduce patients' risk of death. Currently, the identification of HS relies on macrocirculation indicators such as systolic blood pressure and heart rate, which are easily affected by the body's compensatory functions.

Bayesian predictive model averaging approach to joint longitudinal-survival modeling: Application to an immuno-oncology clinical trial.

In immuno-oncology clinical trials, multiple immunological biomarkers are usually examined over time to comprehensively and appropriately evaluate the efficacy of treatments. Because predicting patients' future survival statuses on the basis of such recorded longitudinal information might be of great interest, joint modeling of longitudinal and time-to-event data has been intensively discussed as a toolkit to implement such a prediction. To achieve a desirable predictive performance, averaging over multiple candidate predictive models to account for the model uncertainty might be a more suitable statistical approach than selecting the single best model.

MIZ1 acts downstream of PGM1 in regulating root hydrotropism.

The MIZ1 play an important role in root hydrotropism. However, the relationship between MIZ1-regulated hydrotropism and amyloplast-mediated gravitropism remain largely unclear. Here, we generated the miz1/pgm1 double mutants by crossing the non-hydrotropic miz1 mutant with the amyloplast-defective pgm1 mutant, which lacks gravitropic response.

Synthesis and Study of Photothermal Properties of a Mixed-Valence Nanocluster Cu/Cu with Strong near-Infrared Optical Absorption Supported by 4--Butylcalix[4]arene Ligand.

The first mixed-valence nanocluster Cu/Cu with the highest percentage of Cu ions was synthesized by using 4--butylcalix[4]arene (Calix4), with the formula DMF⊂[(CO)@CuCu(Calix4)Cl(DMF)(HO)]•DMF (), as a photothermal nanocluster. Its structure was characterized using single-crystal X-ray diffraction, Fourier-transform infrared spectroscopy, and powder X-ray diffraction. In addition, the charge state and chemical composition of the nanocluster were determined using electrospray ionization spectrometry and X-ray photoelectron spectroscopy (XPS) spectrum.

Effects of virtual reality in the early-stage stroke rehabilitation: A systematic review and meta-analysis of randomized controlled trials.

Background: Virtual reality (VR) is an emerging technology and has shown promising outcomes in stroke rehabilitation. VR can create an enriched environment, facilitate task-specific training, and provide multimodal sensorimotor feedback to augment functional recovery by driving the experience-dependent plasticity, which is prominent in the early-stage after stroke.

Purpose: This review aimed to systematically identify and examine the feasibility and effectiveness of VR intervention applied within one-month after stroke on functional outcomes of patients.

Construction of eight mixed-valence pentanuclear CuI4Cu clusters using ligands with inhomogeneous electron density distribution: synthesis, characterization and photothermal properties.

To enhance light absorption in the visible region for the utilization of sunlight, eight mixed-valence polynuclear Cu/Cu clusters have been synthesized for evaluating their photothermal conversion performance. They are fabricated considering the ligand's electron density distribution inhomogeneity using 1,2,3-triazole (3N) or tetrazole (4N) and different mono-phosphine ligands. We report here the synthesis, crystal structure, characterization, optical properties, and photothermal conversion performance of these clusters.

Acute oral toxicity test and assessment of combined toxicity of cadmium and aflatoxin B in kunming mice.

Cadmium and aflatoxin B (AFB) are both common and widespread pollutants in food and feed. There are several reports on toxicity induced by Cadmium or AFB alone, but few address the toxicity caused by co-exposure to the two substances. In this study, 42 female and 42 male Kunming (KM) mice were divided into seven groups to test the acute oral toxicity of CdCl and AFB, using Karber's method.