Publications by authors named "Zixuan Liu"

Article Synopsis
  • Five new aerobic, Gram-negative bacterial strains were isolated from coastal soil at LungmuCo Lake in Tibet and are proposed as novel species based on genetic analyses.
  • Phylogenetic and genetic comparisons indicated these strains had high similarity to existing strains but were below the species delineation threshold.
  • Key characteristics included a unique genomic DNA G+C content, specific major polar lipids, and predominant fatty acids, leading to the proposal of the new species name for the strains, with C3-2-a3 identified as the type strain.
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The paper addresses the economic operation optimization problem of photovoltaic charging-swapping-storage integrated stations (PCSSIS) in high-penetration distribution networks. It proposes a dual-layer optimization scheduling model for PCSSIS clusters and distribution network systems. Firstly, a master-slave game model is constructed.

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  • Organic cathode materials are promising for aqueous zinc-ion batteries (AZIBs) due to their low cost and tunable properties, with benzothiadiazoles showing potential for effective electron acceptance.
  • A new polymer, PBDQ-N, was designed by adding nitro groups to enhance electron delocalization and increase active sites, resulting in better zinc-ion insertion/extraction.
  • PBDQ-N exhibited exceptional electrochemical performance with a specific capacity of 446.2 mAh/g and a cycle life of over 20,000 cycles, highlighting the importance of molecular design in optimizing battery materials.
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The supervision of novel psychoactive substances (NPSs) is a global problem, and the regulation of NPSs was heavily relied on identifying structural matches in established NPSs databases. However, violators could circumvent legal oversight by altering the side chain structure of recognized NPSs and the existing methods cannot overcome the inaccuracy and lag of supervision. In this study, we propose a scaffold and transformer-based NPS generation and Screening (STNGS) framework to systematically identify and evaluate potential NPSs.

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Background: Ulcerative colitis (UC) is a chronic non-specific inflammatory intestinal disease, categoried under "dysentery" and "intestinal bleeding" in Traditional Chinese Medicine (TCM). Jianpi Qingchang decoction (JPQC) is a combination formula specifically designed for the treatment of UC. The primary objective of this study is to examine the clinical efficacy of JPQC in individuals diagnosed with UC who exhibit both spleen deficiency and dampness-heat syndrome, along with the presence of fatigue.

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Biomimetic vision is a promising method for efficient navigation and perception, showing great potential in modern navigation systems. Optical flow information, which comes from changes in an image on an organism's retina as it moves relative to objects, is crucial in this process. Similarly, the star sensor is a critical component to obtain the optical flow for attitude measurement using sequences of star images.

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Objective: This study aimed to explore how dyadic coping (DC) influences the psychological resilience (PR) levels of patients with cervical cancer (CC) and their spouses.

Methods: From April to June 2024, this cross-sectional study involved 177 dyads of patients with CC and their spouses from the gynecology and oncology wards of two tertiary hospitals in Xinjiang. Data were collected through questionnaires on demographic information, clinical characteristics, the Resilience Scale, and the Dyadic Coping Inventory, all of which were self-report measures.

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L. (POL) has a long history of medicinal use worldwide, and numerous clinical and experimental studies demonstrated the therapeutic effects of POL and its active ingredients in the treatment of Ulcerative colitis (UC). In this review, we summarized the underlying mechanisms and roles of POL in UC treatment based on experimental and clinical studies.

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Background: Juvenile xanthogranuloma is a rare condition, and femoral involvement is even rarer. We report a case of juvenile xanthogranuloma affecting the femur. To the best of our knowledge, this is the first reported case of femoral juvenile xanthogranuloma in China.

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Objection: The rapid advancement of artificial intelligence has brought significant breakthroughs to various medical disciplines,This study aimed to compare perioperative factors and postoperative hip function recovery in primary total hip arthroplasty (THA)by evaluating the use of an artificial intelligence (AI) preoperative planning system versus traditional two-dimensional X-ray planning.

Patients And Methods: A total of 45 eligible patients underwent primary THA at Beijing Shijitan Hospital, Capital Medical University, between July 2022 and August 2022. The patients were randomly assigned to either the experimental group (n = 19) or the control group (n = 26).

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is a genus of hazardous pathogens that has caused over 30 outbreaks. However, currently approved therapies are limited in scope, as they are only effective against the Ebola virus and lack cross-protection against other orthoebolaviruses. Here, we demonstrate that a previously isolated human-derived antibody, 2G1, can recognize the glycoprotein (GP) of every orthoebolavirus species.

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Renal glomeruli have traditionally been studied by micrometer-scale optical microscopy to interrogate overall physiology or molecular distributions and by nanoscale electron microscopy to interrogate the ultrastructure of thin sections. While these approaches are powerful, they have been limited in their ability to obtain detailed views of the glomeruli as holistic 3D functional units. To fill this knowledge gap, we have developed a novel pipeline for imaging, reconstructing, and analyzing whole mouse glomeruli at 100 nm resolution using super-resolution fluorescence microscopy.

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Introduction: This research aimed to explore the determinants of cervical HPV infection and evaluate how cervical cancer screening outcomes influence sexual functioning and anxiety among women across three provinces in China.

Methods: Study participants were categorized into HPV-positive or HPV-negative groups, after which they completed the General Characteristics Questionnaire and the SAS Anxiety Scale. The HPV-positive cohort was further divided into four subgroups: Subgroup 1 consisted of individuals with HPV types 16 or 18 but no cytological abnormalities.

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Cerenkov radiation-induced photodynamic therapy (CR-induced PDT) has shown the potential to overcome the light penetration limitation in conventional PDT. In addition, the tumor-associated antigens (TAAs) produced by PDT can initiate an antitumor immune process but only show a limited immunotherapeutic effect without the use of immunotherapeutic agents. Herein, a CR-induced PDT hydrogel (R837/Zr-HG-PpIX) has been developed by in situ formation of a hyaluronic acid (HA)-based hydrogel integrated with internal light source Zr, photosensitizer protoporphyrin IX (PpIX), and immune adjuvant imiquimod (R837).

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Article Synopsis
  • Abdominal pain is a key symptom of inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, greatly affecting patients' quality of life.
  • The review analyzes recent research over the last decade regarding the epidemiology, pathophysiology, and management strategies for abdominal pain in IBD.
  • It highlights emerging trends, challenges, and advancements in understanding how abdominal pain relates to disease progression and treatment options for IBD patients.
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The utilization of SPI-Flash in embedded systems is widespread, primarily serving as program storage during the boot process. As a result, the boot process is influenced to some extent by the SPI-Flash controller. This paper presents a lightweight SPI-Flash controller that simplifies the boot process design by establishing a direct connection between the SPI-Flash and AHB-lite bus interface, enabling rapid program execution in RAM instead of directly from the SPI-Flash.

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Mercury, particularly in its methylated form, poses a significant environmental and health risk in aquatic ecosystems. While the toxicity and bioaccumulation of mercury are well documented, there remains a critical gap in our understanding of the mechanisms governing mercury methylation and demethylation in aquatic environments. This review systematically examines the complex interplay of chemical, biological, and physical factors that influence mercury speciation and transformation in natural water systems.

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Article Synopsis
  • Heparin-binding protein (HBP) levels are found to be higher in patients with sepsis and linked to a higher risk of developing disseminated intravascular coagulation (DIC).
  • A study involving 538 sepsis patients identified a cutoff level of 37.5 ng/mL for HBP, which indicated a significant association with DIC and other biomarkers.
  • HBP was shown to activate the TGF-β signaling pathway, leading to increased levels of fibrinogen and plasminogen activator inhibitor-1 (PAI-1), which may contribute to coagulation complications in sepsis.
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Herein, we present a strategy for promoting the cyclization of -aryl or alkenyl arylketone oxime ethers C-N bonds using TEMPO as a direct hydrogen atom transfer (HAT) catalyst. The reaction employs a green solvent and requires no introduction of metal additives. It only needs catalytic amount of TEMPO to drive the reaction.

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  • Traditional dressings often struggle with moisture absorption and can stick to wounds, highlighting the need for improved medical dressings.
  • A new nanofiber membrane made from PLA/PVP and drug-loaded with salicylic acid was developed using electrospinning and UV crosslinking, resulting in a more uniform fiber diameter and enhanced properties like increased porosity.
  • The newly created membrane demonstrated strong antibacterial activity against Escherichia coli and Staphylococcus aureus, while also promoting cell growth, suggesting it could serve as a more effective alternative for medical dressings.
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Article Synopsis
  • A novel bacterial strain, C22-A2, was isolated from Lake LungmuCo in Tibet, characterized as long rod-shaped, Gram-negative, and capable of growth in specific temperature and salinity conditions.
  • Phylogenetic analysis revealed that C22-A2 is related to the genus but distinct enough to be considered a new species, showing high similarity to DSM 10037, yet significant genetic differences from related species.
  • Genome analysis identified genes in C22-A2 that help it withstand osmotic and oxidative stress, alongside shared biochemical traits, leading to its classification as a new species of the genus, officially named sp. nov.
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The outstanding catalytic properties of single-atom catalysts (SACs) stem from the maximum atom utilization and unique quantum size effects, leading to ever-increasing research interest in SACs in recent years. Ru-based SACs, which have shown excellent catalytic activity and selectivity, have been brought to the frontier of the research field due to their lower cost compared with other noble catalysts. The synthetic approaches for preparing Ru SACs are rather diverse in the open literature, covering a wide range of applications.

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Antimicrobial wound dressings can aid wound healing by preventing bacterial infection. This is particularly true of electrospun ones, which have a porous structure and can be easily loaded with antimicrobial drugs. Here, Poly lactic acid (PLA), Silk Fibroin (SF) and antimicrobial agents of Silver nanoparticles (Ag NPs) and Silver oxide (AgO) to prepare the PLA/SF composites antimicrobial nanofiber membrane by electrospinning.

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Magnaporthe oryzae (M. oryzae) is a devastating hemibiotrophic pathogen. Its biotrophic invasive hyphae (IH) are enclosed in the extrainvasive hyphal membrane produced by plant cells, thus generating a front line of the battlefield between the pathogen and the host plants.

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Protein tyrosine phosphatase SHP2 activates RAS signaling, which is a novel target for colorectal cancer (CRC) therapy. However, SHP2 inhibitor monotherapy is ineffective for metastatic CRC and a combination therapy is required. In this study, we aimed to improve the antitumor efficacy of SHP2 inhibition and try to explore the resistance mechanism of SHP2 inhibitor.

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