Burden of Atrial Fibrillation and Atrial Flutter From 1990 to 2021 in China: Global Burden of Disease Study 2021 Update.

Background: Atrial fibrillation (AF) and atrial flutter (AFL) represent increasingly significant health burden globally. We aimed to systematically evaluate the status and trends of AF/AFL burden and attributable risk factors in China.

Methods: We assessed the burden of AF/AFL measured as prevalence, incidence, mortality, and disability-adjusted life years (DALYs), by sex and age groups in China based on the Global Burden of Diseases Study (GBD) 2021 project.

Sex difference in the relationship between childhood obesity and abnormal lipid profiles in young adults.

Background: Abnormal lipid profiles are a major risk factor for cardiovascular diseases, and childhood obesity has been linked to changes in lipid metabolism in adults. However, the relationship between childhood obesity and adult lipid profiles, as well as the potential sex differences, remain unclear. This study aimed to examine the association between childhood obesity and abnormal lipid metabolism in young adults, specifically focusing on sex differences.

Research on upper limb rehabilitation assessment model based on belief rule base.

Rehabilitation assessments hold an irreplaceable role in the field of rehabilitative therapy. However, due to the subjectivity of traditional physicians and the variability of patient conditions, this leads to a lack of detailed grading and inaccurate assessment results. To address this issue, we developed an upper limb rehabilitation evaluation model.

In vitro regulation of collective cell migration: Understanding the role of physical and chemical microenvironments.

Collective cell migration is the primary mode of cellular movement during embryonic morphogenesis, tissue repair and regeneration, and cancer invasion. Distinct from single-cell migration, collective cell migration involves complex intercellular signaling cascades and force transmission. Consequently, cell collectives exhibit intricate and diverse migration patterns under the influence of the microenvironment in vivo.

Cross-Modal self-supervised vision language pre-training with multiple objectives for medical visual question answering.

Medical Visual Question Answering (VQA) is a task that aims to provide answers to questions about medical images, which utilizes both visual and textual information in the reasoning process. The absence of large-scale annotated medical VQA datasets presents a formidable obstacle to training a medical VQA model from scratch in an end-to-end manner. Existing works have been using image captioning dataset in the pre-training stage and fine-tuning to downstream VQA tasks.

Elevated Glucose on Admission Was an Independent Risk Factor for 30-Day Major Adverse Cardiovascular Events in Patients with STEMI but Not NSTEMI.

Background: The purpose of this study was to evaluate the impact of glucose levels on admission, on the risk of 30-day major adverse cardiovascular events (MACEs) in patients with acute myocardial infarction (AMI), and to assess the difference in outcome between ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation myocardial infarction (NSTEMI) patients.

Methods: This study was a post hoc analysis of the Acute Coronary Syndrome Quality Improvement in Kerala Study, and 13,398 participants were included in the final analysis. Logistic regression models were used to assess the association between glucose levels on admission and the risk of 30-day MACEs, adjusting for potential confounders.

Association between the preprocedural serum potassium level and atrial fibrillation recurrence after catheter ablation.

Background: The association between serum potassium and atrial fibrillation (AF) recurrence after catheter ablation remains unclear.

Objective: The purpose of this study was to investigate whether preprocedural serum potassium level influences AF recurrence in patients who underwent catheter ablation.

Methods: We used data of patients with AF who underwent de novo catheter ablation from the prospective Chinese Atrial Fibrillation Registry Study.

Small Left Ventricle in Patients With Atrial Fibrillation Is Associated With Increased Cardiovascular Risk.

Background: It is still unclear whether small left ventricle (LV) is an adverse structural prognostic feature in patients with atrial fibrillation (AF).

Objectives: The purpose of this study was to evaluate the association between small LV and risk of cardiovascular events in AF population.

Methods: From the China-AF registry, 7,764 patients with AF were enrolled and divided into groups with normal, small, and large LV size based on left ventricular end-diastolic dimension (LVEDD) measurement per the American Society of Echocardiography references.

Hierarchical porous carbon materials for lithium storage: preparation, modification, and applications.

Secondary battery as an efficient energy conversion device has been highly attractive for alleviating the energy crisis and environmental pollution. Hierarchical porous carbon (HPC) materials with multiple sizes pore channels are considered as promising materials for energy conversion and storage applications, due to their high specific surface area and excellent electrical conductivity. Although many reviews have reported on carbon materials for different fields, systematic summaries about HPC materials for lithium storage are still rare.

Evaluation of an algorithm-guided photoplethysmography for atrial fibrillation burden using a smartwatch.

Background: Wearable devices based on the PPG algorithm can detect atrial fibrillation (AF) effectively. However, further investigation of its application on long-term, continuous monitoring of AF burden is warranted.

Method: The performance of a smartwatch with continuous photoplethysmography (PPG) and PPG-based algorithms for AF burden estimation was evaluated in a prospective study enrolling AF patients admitted to Beijing Anzhen Hospital for catheter ablation from September to November 2022.

Association between the ZJU index and risk of new-onset non-alcoholic fatty liver disease in non-obese participants: a Chinese longitudinal prospective cohort study.

Background: Non-alcoholic fatty liver disease (NAFLD) is increasingly observed in non-obese individuals. The ZJU (Zhejiang University) index has been established as a new and efficient tool for detecting NAFLD, but the relationship between the ZJU index and NAFLD within non-obese individuals still remains unclear.

Methods: A evaluation was undertaken using data from a health assessment database by the Wenzhou Medical Center.

Generative adversarial network based on frequency domain data enhancement: Dual-way discriminator structure Copes with limited data.

The excellent image-generation ability of generative adversarial networks (GANs) has been widely used. However, training a GAN requires large-scale data support, which hinders in-depth development. Therefore, the research on stable training of GANs under limited data conditions is helpful to further expand the application scenarios.

Promising application of pulsed electromagnetic fields on tissue repair and regeneration.

Tissue repair and regeneration is a vital biological process in organisms, which is influenced by various internal mechanisms and microenvironments. Pulsed electromagnetic fields (PEMFs) are becoming a potential medical technology due to its advantages of effectiveness and non-invasiveness. Numerous studies have demonstrated that PEMFs can stimulate stem cell proliferation and differentiation, regulate inflammatory reactions, accelerate wound healing, which is of great significance for tissue regeneration and repair, providing a solid basis for enlarging its clinical application.

Regulation of Tendon Stem Cell Behavior by Designed Nanoporous Topography of Microfibers.

Nano scale topography scaffold is more bioactive and biomimetic than smooth fiber topographies. Tendon stem cells (TSCs) play important roles in the tendinogenesis of tendon tissue engineering, but the effects and mechanisms of nano topography on TSC behavior are still unclear. This study determined whether the morphology, proliferation, cytoskeleton, and differentiation of TSCs are affected by topography of scaffold in vitro.

Effect of SGLT2 inhibitors on cardiovascular events in patients with atrial fibrillation: A systematic review and meta-analysis of randomized controlled trials.

Background: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) is reported to reduce incident atrial fibrillation (AF) in patients with or without diabetes; however, its cardiovascular (CV) benefit for AF patients remains unclear.

Ss Aims: To investigate the effect of SGLT2i on the incidence of CV events in patients with AF.

Methods: Six randomized controlled trials (RCTs) assessing the effects of SGLT2i on CV outcomes in patients with or without AF were included (PROSPERO: CRD 42023431535).

YOLO-G: Improved YOLO for cross-domain object detection.

Cross-domain object detection is a key problem in the research of intelligent detection models. Different from lots of improved algorithms based on two-stage detection models, we try another way. A simple and efficient one-stage model is introduced in this paper, comprehensively considering the inference efficiency and detection precision, and expanding the scope of undertaking cross-domain object detection problems.

The regulation of tendon stem cell distribution, morphology, and gene expression by the modulus of microfibers.

The mechanical properties of a stem cell culture substrate significantly impact cell adhesion, survival, migration, proliferation, and differentiation in vitro. A major challenge in engineering artificial stem cell substrate is to properly identify the relevant physical features of native stem cell niches, which are likely different for each stem cell type. The behavior of tendon stem cells has potentially significant implications for tendon repair.

Unexpectedly Efficient Aging of Organic Aerosols Mediated by Autoxidation.

Multiphase oxidative aging is a ubiquitous process for atmospheric organic aerosols (OA). But its kinetics was often found to be slow in previous laboratory studies where high hydroxyl radical concentrations ([OH]) were used. In this study, we performed heterogeneous oxidation experiments of several model OA systems under varied aging timescales and gas-phase [OH].

Peroxy Radical Autoxidation and Sequential Oxidation in Organic Nitrate Formation during Limonene Nighttime Oxidation.

Limonene is an abundant monoterpene released into the atmosphere via biogenic emissions and biomass burning. However, the atmospheric oxidation and secondary organic aerosol (SOA) formation mechanisms of limonene, especially during nighttime, remain largely understudied. In this work, limonene was oxidized synergistically by ozone (O) and nitrate radicals (NO) in a flow tube reactor and a continuous flow stirred tank reactor.

Robust Lidar-Inertial Odometry with Ground Condition Perception and Optimization Algorithm for UGV.

Unmanned ground vehicles (UGVs) are making more and more progress in many application scenarios in recent years, such as exploring unknown wild terrain, working in precision agriculture and serving in emergency rescue. Due to the complex ground conditions and changeable surroundings of these unstructured environments, it is challenging for these UGVs to obtain robust and accurate state estimations by using sensor fusion odometry without prior perception and optimization for specific scenarios. In this paper, based on an error-state Kalman filter (ESKF) fusion model, we propose a robust lidar-inertial odometry with a novel ground condition perception and optimization algorithm specifically designed for UGVs.