Objectives: The impact of rheumatic diseases, long-term medication, and vaccination on COVID-19 severity remain insufficiently understood, hindering effective patient management. This study aims to investigate factors influencing COVID-19 severity in Chinese rheumatic patients and to provide real-world evidence for patient care.
Methods: We conducted a retrospective observational study consisting of two cohorts, followed by a nested case-control analysis.
Vaccines (Basel)
September 2022
The coronavirus disease 2019 (COVID-19) pandemic has imposed enormous morbidity and mortality burdens. Patients with rheumatic diseases (RDs) are vulnerable to the COVID-19 infection, given their immunocompromised status. Ensuring acceptance of the COVID-19 vaccine is important and has attracted attention by health professionals.
View Article and Find Full Text PDFBackground: Cardiac involvement is a major cause of death in SSc, while early detection remains a challenge.
Objectives: The purpose of this study was to investigate the prevalence and clinical implications of cardiac impairment in SSc.
Methods: Ninety-five consecutive SSc patients [55.
Objectives: Scleroderma renal crisis (SRC) is a life-threatening syndrome. The early identification of patients at risk is essential for timely treatment to improve the outcome. Therefore, it is of great interest to provide a personalised tool to predict risk of SRC in systemic sclerosis (SSc).
View Article and Find Full Text PDFObjectives: The impact of rheumatic diseases on COVID-19 infection remains poorly investigated. Here we performed a systematic review and meta-analysis to evaluate the outcomes of COVID-19 in patients with rheumatic diseases.
Methods: We systematically searched PubMed, Embase, Cochrane Library, Scopus and preprint database up to 29th August 2020, for publications with confirmed COVID-19 infection in patients with rheumatic diseases.