Publications by authors named "Zitong Wan"

Background And Objective: Pulmonary nodules (PNs) are small (≤3 cm) radiographic opacities within lung parenchyma. The use of low-dose computed tomography (LDCT) has led to a significant increase in the identification of solitary nodules. Malignant lung nodules comprise only 5% of all nodules, with management differing greatly from benign cases.

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Article Synopsis
  • - Multiple primary lung cancer (MPLC) is becoming more common and is classified into synchronous (sMPLC) and metachronous (mMPLC) types, which require careful differentiation from intrapulmonary metastases (IPM) for proper treatment.
  • - Diagnosis of MPLC relies on histology, imaging, and molecular methods, with imaging being crucial for preoperative assessments and histology providing definitive diagnoses.
  • - Surgical intervention is the primary treatment option, supplemented by techniques like stereotactic radiotherapy and ablation for lesions that can't be surgically removed; targeted therapies and immunotherapies may also be used, highlighting the importance of a multidisciplinary approach in treatment planning.
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Objective: This study aimed to investigate TCF19's role in lung cancer development, specifically its involvement in the RAF/MEK/ERK signaling pathway.

Methods: Lung cancer tissue analysis revealed significant TCF19 overexpression. In vitro experiments using A549 and Hop62 cells with TCF19 overexpression demonstrated enhanced cell growth.

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Motor imagery (MI) aims to use brain imagination without actual body activities to support motor learning, and machine learning algorithms such as common spatial patterns (CSP) are proven effective in the analysis of MI signals. In the conventional machine learning-based approaches, there are two main difficulties in feature extraction and recognition of MI signals: high personalization and data fading. The high personalization problem is due to the multi-subject nature when collecting MI signals, and the data fading problem as a recurring issue in MI signal quality is first raised by us but is not widely discussed at present.

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