Epidermal growth factor receptor (EGFR) homodimers and heterodimers play significant roles in a variety of tumors, but current imaging probes remain problematic due to restricted contrast and sensitivity. Thus, we have developed aptamer-mediated activated conformational transitions to target the EGFR and HER2. Furthermore, based on signal amplification techniques, especially the FRET fluorescence enhancement properties of poly-β-CD, supramolecular FRET signal amplification nanoprobes were constructed to improve imaging contrast and sensitivity.
View Article and Find Full Text PDFSoil, plant, and water, as well as trace elements they contain, can influence human health through the food chain. A survey was conducted on distributions of trace elements in soils, plants, and drinking water in Rugao County, Jiangsu Province, China, an agricultural area with a high level of centenarians and nonagenarians. The ratio of people over 90 years old per 100,000 inhabitants (90-rate) based on village (about 4,000 residents in 4 km(2)) was correlated with trace elements in soil, drinking water, and rice by means of correlation analysis and/or principal component analysis.
View Article and Find Full Text PDFThis investigation selected the city of Nanjing, Jiangsu province of China, as the study area, and analyzed the concentrations of organic carbon (OC) and black carbon (BC) of ten soils profiles in three different groups, by wet chemical oxidation methods. The results showed that the concentration of BC ranged from 0.22 g x kg(-1) to 32.
View Article and Find Full Text PDFYing Yong Sheng Tai Xue Bao
January 2006
Ying Yong Sheng Tai Xue Bao
January 2004
The concentration and source of heavy metals in Nanjing urban soils and their relationships with soil properties were studied. The results indicated that the soils in Nanjing urban were not obviously polluted by Fe, Ni, Co and V, but polluted by Mn, Cr, Cu, Zn, and Pb to a certain extent. The heavy metals were irregularly distributed in soil profiles.
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