Research on quantitative evaluation of medical insurance fraud supervision policy based on 'Antecedents-Process-Outcomes' framework.

Fraud in medical insurance is a serious problem that threatens the safety and sustainability of medical insurance funds. The process of reducing or even eliminating the impact of fraud is related to maintaining the balance of payments for medical insurance funds and reforming the payment system based on total amount control. As a result of reviewing the policy background of medical insurance fraud in China, combined with the policy evaluation model in the area of public management, this paper develops a conceptual framework of 'Antecedents-Process-Outcomes' that emphasizes the fraud and governance of medical insurance funds.

PAK2 as a therapeutic target in cancer: Mechanisms, challenges, and future perspectives.

P21-activated kinases (PAKs) are crucial regulators within cellular signaling pathways and have been implicated in a range of human diseases, including cancer. Among the PAK family, PAK2 is widely expressed across various tissues and has emerged as a significant driver of cancer progression. However, systematic studies on PAK2 remain limited.

Mitotic Functions and Characters of KIF11 in Cancers.

Mitosis mediates the accurate separation of daughter cells, and abnormalities are closely related to cancer progression. KIF11, a member of the kinesin family, plays a vital role in the formation and maintenance of the mitotic spindle. Recently, an increasing quantity of data have demonstrated the upregulated expression of KIF11 in various cancers, promoting the emergence and progression of cancers.

FeO Embedded in N-Doped Porous Carbon Derived from Hemin Loaded on Active Carbon for Supercapacitors.

The high power density and long cyclic stability of N-doped carbon make it an attractive material for supercapacitor electrodes. Nevertheless, its low energy density limits its practical application. To solve the above issues, FeO embedded in N-doped porous carbon (FeO/N-PC) was designed by pyrolyzing Hemin/activated carbon (Hemin/AC) composites.

Diffusive exit rates through pores in membrane-enclosed structures.

The function of many membrane-enclosed intracellular structures relies on release of diffusing particles that exit through narrow pores or channels in the membrane. The rate of release varies with pore size, density, and length of the channel. We propose a simple approximate model, validated with stochastic simulations, for estimating the effective release rate from cylinders, and other simple-shaped domains, as a function of channel parameters.

MRI-visible enlarged perivascular spaces: imaging marker to predict cognitive impairment in older chronic insomnia patients.

Objective: Perivascular spaces (PVS), components of the glymphatic system in the brain, have been known to be important conduits for clearing metabolic waste, and this process mainly increases during sleep. Sleep disruption might result in PVS dysfunction and cognitive impairment. In this study, we aim to explore whether MRI-visible enlarged perivascular spaces (EPVS) could be imaging markers to predict cognitive impairment in chronic insomnia patients.

New Covalent Triazine Framework Rich in Nitrogen and Oxygen as a Host Material for Lithium-Sulfur Batteries.

Lithium-sulfur (Li-S) batteries have been widely considered as the next-generation energy storage system but hindered by the soluble polysulfide intermediate-induced shuttle effect. Doping heteroatoms was confirmed to enhance the affinity of polysulfide and the carbon host, release the shuttle effect, and improve the battery performance. To enhance the Lewis acidity and reinforce the interaction between polysulfide and the carbon skeleton, a novel covalent triazine framework (CTFO) was designed and fabricated by copolymerizing 2,4,6-triphenoxy--triazine and 2,4,6-trichloro-1,3,5-triazine through Friedel-Crafts alkylation.

The distribution of Mn2+ in rabbit eyes after topical administration for manganese-enhanced MRI.

Purpose: To analyze the distribution of Mn(2+) in rabbit eyes after topical administration of Mncl2 for manganese-enhanced MRI.

Methods: Forty-eight Chinese white rabbits were divided into three groups. In group 1 (n = 4), the baseline concentration of Mn(2+) in aqueous, vitreous and serum samples were analyzed.