Publications by authors named "Zisong Xie"

Article Synopsis
  • - Varicocele is a common condition affecting 10% to 15% of adult males, often causing scrotal pain and testicular issues, with treatments ranging from medication to surgery.
  • - Surgical treatment is the most effective option with an 80% success rate, but it comes with risks like bleeding, infection, and recurrence.
  • - Recently, transcutaneous neuromuscular electrical stimulation has emerged as a non-invasive alternative for alleviating varicocele-induced pain, showing positive results and highlighting the need for more research to confirm its effectiveness and safety.
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Background And Objective: Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme involved in folate metabolism and one-carbon metabolism. MTHFR gene polymorphism affects enzyme activity. MTHFR gene polymorphism is closely related to many human diseases, such as cardiocerebrovascular diseases, diabetes, neural tube defects (NTDs), tumors, and so on.

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Objective: To investigate the clinical efficacy of dapoxetine combined with transcutaneous neuromuscular electrical stimulation (TNES) in the treatment of primary premature ejaculation.

Methods: A total of 60 patients who met the diagnostic criteria for primary premature ejaculation were selected as study subjects and randomly divided into a dapoxetine group (control group) and a dapoxetine combined with percutaneous neuromuscular electrical stimulation group (observation group).30 patients in each group were treated for 4 weeks.

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