Synopsis of recent research by authors named "Zirui Wan"
- Zirui Wan's recent research predominantly focuses on stem cell biology, exploring the generation of human induced pluripotent stem cells (iPSCs) and human embryonic stem cells (hESCs) for potential applications in disease modeling and genetic disease understanding, as seen in the development of specific cell lines for investigating conditions like Alagille syndrome.
- The author has also contributed to the fields of pharmacogenomics and metabolic studies, particularly evaluating how genetic polymorphisms affect drug responses and therapeutic outcomes, which is evidenced by studies on olanzapine and gefitinib pharmacokinetics in different populations.
- Additional research by Zirui Wan delves into the interplay between infectious diseases, such as cytomegalovirus, and various conditions like atherosclerosis and inflammatory bowel disease, highlighting the complex relationships between viral infections and chronic inflammatory responses in disease progression.
