polysaccharide remodels colon inflammatory microenvironment and improves gut health.

Aim: Disturbed intestinal microbiota has been implicated in the inflammatory microenvironment of the colon, which usually results in ulcerative colitis (UC). Given the limitations of these drugs, it is important to explore alternative means of protecting the gut health from UC. This study aimed to investigate the potential of polysaccharides as beneficial nutrients in the regulation of the gut microbiota, which determines the inflammatory microenvironment of the colon.

Chitosan nanocomposite films based on halloysite nanotubes modification for potential biomedical applications.

Chitosan is attracting increasing attention for biomedical applications because of its biocompatibility. In the present study, raw halloysite nanotubes (RHNTs) were functionalised with (3-aminopropyl) triethoxysilane (APTS) and then a sequence of novel chitosan biofilms were prepared by adding amino-modified halloysite nanotubes (HNTs-NH) as a reinforcing material and ethylene glycol diglycidyl ether (EGDE) as a cross-linking agent. The reaction between the APTS and the RHNTs was demonstrated through characterisation of the HNTs-NH.