mA reader YTHDF2 orchestrates CD8 T cell infiltration to promote pancreatic cancer progression and predicts clinical outcome.

Pancreatic cancer has emerged as one of the most lethal malignancies, characterized by rising morbidity and mortality rates. Research has demonstrated that N6-methyladenosine (mA) modification of RNA significantly influences RNA metabolism, and dysregulation of mA is implicated in various human diseases. A clearer picture of how the divergent mA methylation patterns affect immunological microenvironment in pancreatic cancer is still unknown.

Adjuvant transarterial chemoembolization timing after radical resection is an independent prognostic factor for patients with hepatocellular carcinoma.

Background: It has been reported that postoperative adjuvant TACE (PA-TACE) treatment decreases recurrence and significantly improves the survival of patients who undergo radical resection of hepatocellular carcinoma (HCC) with high-risk recurrence factors. However, when to perform PA-TACE has not been fully studied.

Methods: We retrospectively collected the clinicopathologic characteristics of the patients with HCC between October 2013 and June 2020.

Environmental impact assessment of wastewater discharge with multi-pollutants from iron and steel industry.

The iron and steel industry discharges large quantities of wastewater. The environmental impact of the wastewater is traditionally assessed from the quantitative aspect. However, the water quality of discharged wastewater plays a more significant role in damaging the natural environment.