Efficient synthesis of polycarbonate ether polyol copolymerization of CO and 1,2-butylene oxide over a layered Zn-Co double metal cyanide catalyst.

Polycarbonate ether polyol synthesized by the copolymerization of carbon dioxide (CO) and epoxides is a promising technology for chemically fixing CO and manufacturing degradable polymeric materials. However, research on the copolymerization of CO and 1,2-butylene oxide (BO) to produce polycarbonate ether polyol is relatively scarce. Herein, we employed layered Zn-Co double metal cyanide (L-DMC) as a catalyst for the copolymerization of CO and BO to obtain polycarbonate ether polyol.

Carrying both the heterozygous Myh6-R453C and Tnnt2-R92W mutations aggravate the hypertrophic cardiomyopathy phenotype in mice.

Hypertrophic cardiomyopathy (HCM) is an inherited disease of the heart muscle that is dominated by variations in eight genes encoding sarcomere proteins. Although there are clinical or basic research reports that carrying double mutations can lead to more severe HCM phenotypes, there are also research reports that after reanalyzing the reported mutations, the severity of clinical symptoms in patients with double mutations did not significantly increase compared to patients with only one mutation. To determine whether double pathogenic mutations can aggravate the phenotype of hypertrophic cardiomyopathy in mice, we constructed mice carrying single pathogenic heterozygous mutation Myh6-R453C or Tnnt2-R92W and mice carrying both pathogenic heterozygous mutations.

Traditional bullying, cyberbullying, and quality of life among adolescents in 35 countries: Do cultural values matter?

Rationale: Substantial evidence indicates that involvement in school bullying has been linked to lower quality of life (QoL). Yet there is little information elucidating the link between bullying involvement and QoL in different cultures.

Objective: This study investigated the associations between different types of bullying involvement and QoL among adolescents.

Injectable Living Probiotic Dressing Built by Droplet-Based Microfluidics and Photo-Cross-Linking to Prevent Pathogenic Infection and Promote Wound Repair.

The treatment of infected wounds faces great challenges due to the emergence of antibiotic resistance and the lack of persistence in drug release. Here, a living probiotic dressing is constructed by integrating droplet-shearing and photo-cross-linking. Saccharomyces boulardii (S.

Antifungal bio-coating of endotracheal tube built by overexpressing the MCP1 gene of Saccharomyces boulardii and employing hydrogel as a "house" to antagonize Candida albicans.

Background: For some ICU patients, an artificial airway must be established with an endotracheal tube, but Candida albicans can easily adhere to the tube surface and form a biofilm, leading to potentially life threatening fungal infections. Therefore, it is urgent to prevent and reduce C. albicans infections introduced by the endotracheal tube.

Analysis of long noncoding RNAs expression profiles in the human cardiac fibroblasts with cardiac fibrosis.

Cardiac fibrosis is a common pathological feature of cardiac remodelling process with disordered expression of multiple genes and eventually lead to heart failure. Emerging evidence suggests that long noncoding RNAs (lncRNAs) have emerged as critical regulators of various biological processes. However, the exact mechanisms of lncRNAs as mediators in cardiac fibrosis have not been fully elucidated.

Trust in Government, Perceived Integrity and Food Safety Protective Behavior: The Mediating Role of Risk Perception.

This study examined the correlations between trust in government and the public's protective behaviors regarding food safety, focusing on the mediating role of risk perception. The 2013 (1,432 samples) and 2019 (1,276 samples) Taiwan Social Change Survey data were analyzed using ordinary least squares regression models. The bootstrap method was used to examine the mediating effect of risk perception.

Sequential hydrogenation of nitroaromatics to alicyclic amines highly-dispersed Ru-Pd nanoparticles anchored on air-exfoliated CN nanosheets.

Developing efficient and green catalytic systems is highly desired in the syntheses of alicyclic amines hydrogenation of nitroaromatics. Herein, we developed Ru-Pd dual active site catalysts in which Ru and Pd species were anchored and highly dispersed on air-exfoliated carbon nitride (Ru-Pd/CN-air). As-prepared catalysts were employed in the hydrogenation of nitrobenzene (NB) to cyclohexylamine (CHA).

Prognostic efficacy and prognostic factors of TACE plus TKI with ICIs for the treatment of unresectable hepatocellular carcinoma: A retrospective study.

Hepatocellular carcinoma (HCC) remains a global challenge due to its high morbidity and mortality rates as well as poor response to treatment. Local combined systemic therapy is widely used in the treatment of unresectable hepatocellular cancer (uHCC). This retrospective study was to investigate the prognostic effect and prognostic factors of transcatheter arterial chemoembolization (TACE) plus tyrosine kinase inhibitors (TKI) with immune checkpoint inhibitors (ICIs) in the treatment of uHCC.

Topical and emotional expressions regarding extreme weather disasters on social media: a comparison of posts from official media and the public.

Understanding media frames and the public resonance during disasters is essential for making inclusive climate change and adaptation policies in the context of increasingly extreme weather events. In this study, we use the extreme weather and flood event that occurred in July 2021 in Zhengzhou, China, as a case study to investigate how official media in China reported this event and how the public responded. Moreover, since one accountability investigation report regarding this disaster was released in January 2022, we also compared these posts between the emergency response period and the post-crisis learning period after the report's release.

Associations between school bullying and anxiety in children and adolescents from an ethnic autonomous county in China.

School bullying is a widespread public health issue that negatively impacts the mental health of children and adolescents. This study aimed to investigate associations between school bullying involvement and anxiety of children and adolescents. A survey covering all types of pre-college schools (primary, middle, high, and vocational school) was conducted in an ethnic autonomous county in China.

Validation of the Chinese Version of KIDSCREEN-10 Quality of Life Questionnaire: A Rasch Model Estimation.

The KIDSCREEN-10 was deemed as a cross-national instrument for measuring Health-Related Quality of Life (HRQoL). However, no empirical endeavor has explored its reliability and validity in the context of China. This study aims to translate and validate the Chinese version of the KIDSCREEN-10 questionnaire.

Cyberbullying Involvement, Resilient Coping, and Loneliness of Adolescents During Covid-19 in Rural China.

Cyberbullying involvement can lead to internal health issues, especially mental health problems. Different coping strategies may reduce or enhance the strengths between cyberbullying experience and mental health problems. In this study, we examined the correlations between cyberbullying involvement and loneliness among a group of children and adolescents during the Covid-19 pandemic in China, focusing on investigating the protecting effect of the resilient coping strategy.

Place Attachment and Household Disaster Preparedness: Examining the Mediation Role of Self-Efficacy.

Household preparedness is essential for resilience-building and disaster risk reduction. Limited studies have explored the correlations between place attachment, self-efficacy, and disaster preparedness, especially in the east Asian cultural context. This study investigates the mediating role of self-efficacy between place attachment and disaster preparedness based on data from the 2018 Shandong General Social Survey (N = 2181) in China.

Integrated Analysis of Coding Genes and Non-coding RNAs Associated with Shell Color in the Pacific Oyster (Crassostrea gigas).

Molluscan shell color polymorphism is important in genetic breeding, while the molecular information mechanism for shell coloring is unclear. Here, high-throughput RNA sequencing was used to compare expression profiles of coding and non-coding RNAs (ncRNAs) from Pacific oyster Crassostrea gigas with orange and black shell, which were from an F2 family constructed by crossing an orange shell male with a black shell female. First, 458, 13, and 8 differentially expressed genes (DEGs), lncRNAs (DELs), and miRNAs (DEMs) were identified, respectively.

What Do You Mean by Community Resilience? More Assets or Better Prepared?

Objectives: Understanding people's perception of community resilience to disaster is important. This study explores the correlations of household livelihood assets, the adopted household disaster preparedness activities, and individuals' assessment of community resilience.

Methods: The data was collected in 2018 by surveying a group of survivors affected by the 2008 Wenchuan earthquake in China.

How is COVID-19 Being Contained in China? An Observational Study on the Local Level.

Objective: This article investigates how a Chinese local government responded to the ongoing coronavirus disease 2019 (COVID-19) outbreak, and the lessons can be valuable for the ongoing response efforts worldwide.

Methods: This case study used primarily participant observations and interviews with stakeholders.

Results: We find that nonpharmaceutical interventions, especially the physical distancing measures, are the primary tools used to contain the spread of the virus, and these actions keep changing to adapt to the situation of the local cases and the directions from the central government.

Temporal Dynamics of Public Emotions During the COVID-19 Pandemic at the Epicenter of the Outbreak: Sentiment Analysis of Weibo Posts From Wuhan.

Background: The ongoing COVID-19 pandemic has led to an increase in anxiety, depression, posttraumatic stress disorder, and psychological stress experienced by the general public in various degrees worldwide. However, effective, tailored mental health services and interventions cannot be achieved until we understand the patterns of mental health issues emerging after a public health crisis, especially in the context of the rapid transmission of COVID-19. Understanding the public's emotions and needs and their distribution attributes are therefore critical for creating appropriate public policies and eventually responding to the health crisis effectively, efficiently, and equitably.

Stochastic Petri Net Based Modeling of Emergency Medical Rescue Processes during Earthquakes.

The post-disaster emergency medical rescue (EMR) is critical for people's lives. This paper presents a stochastic Petri net (SPN) model based on the process of the rescue structure and a Markov chain model (MC), which is applied to the optimization of the EMR process, with the aim of identifying the key activities of EMR. An isomorphic MC model is developed for measuring and evaluating the time performance of the EMR process during earthquakes with the data of the 2008 Wenchuan earthquake.

Cyberbullying Involvement and Psychological Distress among Chinese Adolescents: The Moderating Effects of Family Cohesion and School Cohesion.

Cyberbullying and its consequences is a little-investigated public health issue. We investigated the correlations between cyberbullying involvement, either being a victim or being a preparator, and psychological distress among a group of Chinese adolescents. A representative sample of 4978 students from Jiangsu province covering all types of pre-college schools was surveyed using a stratified sampling method.

How investment in public health has impacted the prevalence of tuberculosis in China: A study of provincial variations between 2005 and 2015.

How do public investments in public health actually impact health outcomes? This question has not been investigated enough, especially regarding infectious diseases. This study investigates the correlations between public health expenditure and the incidence of tuberculosis in China using a provincial panel dataset. The analysis focuses on the correlations between public health expenditure and tuberculosis incidence, using the fixed effects models and Two Stage Least Squares (2SLS) method.

What makes people intend to take protective measures against influenza? Perceived risk, efficacy, or trust in authorities.

Background: Influenza outbreaks occur annually across the world, causing a global health challenge. This study aims to explore the association between risk perception (perceived severity and perceived probability), perceived efficacy (individual's efficacy and government's efficacy), trust in authorities, and intention to implement influenza protective behaviors.

Methods: The data (N = 1,372) used in this paper comes from the 2013 Taiwan Social Change Survey dataset.