Publications by authors named "Ziqi Lian"
Article Synopsis
- Tetraphenylethene (TPE) is a compound with significant applications in creating fluorescent nanomaterials and biosensors, but challenges remain in making TPE aggregates that exhibit strong fluorescence and electrochemiluminescence.*
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- This study presents a highly sensitive bacterial ECL biosensor developed from TPE-based covalent organic polymer nanoparticles, which were synthesized using a straightforward Menschutkin reaction with specific cross-linking agents.*
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- The resulting biosensor demonstrated exceptional sensitivity (0.19 CFU mL detection limit), a wide linear detection range, and impressive ECL efficiency, significantly enhancing its potential for large-scale detection of harmful bacteria.*
Article Synopsis
- Low mass transfer efficiency and matrix effects hinder the development of effective biosensing systems; however, an ultra-rapid detection platform using machine learning and DNA xerogel has been created to detect NGAL, a protein biomarker for acute kidney injury.
- The platform regulates pore sizes in xerogels to enhance NGAL transfer and accelerates reactions due to nanoconfinement effects, achieving rapid detection from human urine in about 5 minutes.
- Additionally, the system allows for one-step detection without sample prep and can be customized for different diseases by modifying DNA sequences or fluorescence intensities.
