Publications by authors named "Ziou Li"
Behavior, hormone, and gut microbiota change by YYNS intervention in an OVX mouse model.
Front Cell Infect Microbiol
November 2024
Article Synopsis
- Perimenopause depression disorder (PDD) is common, characterized by depression and symptoms like hot flashes, linked to low estrogen levels, with emerging research tying it to the endocrine-brain-gut-microbiota axis.
- The study used a mouse model to simulate menopausal depression and tested the effects of a traditional Chinese remedy, Yangyin-ningshen formula (YYNS), alongside estrogen (E2) on behavioral and microbiome changes.
- Results indicated that YYNS significantly alleviated depression symptoms, improved microbial diversity, and altered hormone levels in the OVX mice after three weeks, suggesting its potential role in managing PDD.