Grading of invasive breast carcinoma through Grassmannian VLAD encoding.

In this paper we address the problem of automated grading of invasive breast carcinoma through the encoding of histological images as VLAD (Vector of Locally Aggregated Descriptors) representations on the Grassmann manifold. The proposed method considers each image as a set of multidimensional spatially-evolving signals that can be efficiently modeled through a higher-order linear dynamical systems analysis. Subsequently, each H&E (Hematoxylin and Eosin) stained breast cancer histological image is represented as a cloud of points on the Grassmann manifold, while a vector representation approach is applied aiming to aggregate the Grassmannian points based on a locality criterion on the manifold.

Diagnostic medicine: A comprehensive ABCDE algorithm for accurate interpretation of radiology and pathology images and data.

A pathway to the procedure of interpreting radiology images or pathology slides is presented. This simplified mnemonic can be used as a memory aid determining the order in which diagnosis should be approached. First, before we place the radiology image in front of the lightbox or the slide under the microscope we have to be sure that it is adequately labelled and prepared (Correct).

Extremely rare case of primary cardiac chondroma in a patient presenting with acute pulmonary edema.

Primary tumors of the heart are rare entities, substantially less frequent than cardiac metastases. Primary chondroma is an exceptionally rare cardiac tumor. We describe the case of a patient presenting with acute pulmonary edema with the incidental echocardiographic finding of a large left atrial tumor that was histopathologically diagnosed as primary cardiac chondroma.

Replacement of the uterus by malignant mesothelioma of the peritoneum: a case report.

Malignant mesothelioma of the peritoneum is a rare tumor that must be distinguished from the more common primary peritoneal serous epithelial neoplasms. We report a case of a 66-year-old female presenting with weight loss, anemia, and a large pelvic mass on ultrasound. At laparotomy a large (9 x 6.

Adenoid cystic carcinoma of Bartholin's gland: a case report.

Adenoid cystic carcinoma is an uncommon histological type of the already rare carcinoma of Bartholin's gland with 51 cases described in the literature. We present a case of a 66-year-old woman who was admitted with severe pelvic pain. In an examination under anesthesia a 10x5 cm apparently fixed mass at the left vaginal wall originating from the area of Bartholin's gland was found.

[Collagenolysis above eccrine spiradenoma].

Background: The casual observation of a peritumoral edema with collagenolysis in a case of eccrine spiradenoma led us to search for similar lesions in a retrospective series of 50 spiradenomas.

Material And Methods: Among 50 cases of eccrine spiradenomas, 36 excised with the overlying epidermis and the surrounding dermis were finally available for a conventional histologie study.

Results: In 14 cases, i.

Immunohistochemical detection of ras P21 oncoprotein in human skin lesions.

This study was undertaken to investigate the role of the human ras family gene product [P21] in various benign, precancerous and malignant skin lesions. A streptavidin-biotin peroxidase method was performed using the monoclonal antibody (Mab)Y13259 in paraffin tissue sections of a total of 69 skin lesions (5 benign hyperplasias, 12 seborrheic keratoses, 9 solar keratoses, 20 basal cell carcinomas and 23 squamous cell carcinomas). The adjacent normal skin was also studied in all cases.

Monoclonal antibodies to epithelioid cells in lip biopsy in sarcoidosis.

The phenotype of infiltrating and residual cells in biopsies of minor salivary glands from patients with sarcoidosis and from normal controls, were studied using a sensitive two-step indirect immunoperoxidase technique. We found that infiltrating lymphocytes were practically absent from salivary gland biopsies in the control group, but that in the Sarcoid group the numerous infiltrating lymphocytes consisted mainly of T-lymphocytes, mostly T-helper cells (CD4+ cells). These data correlate positively with other studies on lymphocytic infiltration in other organs involved in the immunopathology of sarcoidosis, e.