Publications by authors named "Zinia Charlotte D'Souza"
Article Synopsis
- - The study explores the role of vimentin expression in premature oral lesions and its contribution to cellular transformation, using both lab-grown cells and animal models.
- - Researchers inserted vimentin into cells and tested transformation with additional carcinogenic agent benzo[a]pyrene (BP), finding that vimentin led to traits related to epithelial-mesenchymal transition (EMT) and stemness.
- - Results showed that high vimentin and low E-cadherin expression were linked to more severe dysplasia and lymph node metastasis in tumors, suggesting vimentin might help identify high-risk lesions in patients.
BPAG1e and Plectin are hemidesmosomal linker proteins which anchor intermediate filament proteins to the cell surface through β4 integrin. Recent reports indicate that these proteins play a role in various cellular processes apart from their known anchoring function. However, the available literature is inconsistent.
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