Chemical Composition, Antifungal and Anti-Biofilm Activities of Volatile Fractions of L. Roots from Tunisia.

The antifungal drugs currently available and mostly used for the treatment of candidiasis exhibit the phenomena of toxicity and increasing resistance. In this context, plant materials might represent promising sources of antifungal agents. The aim of this study is to evaluate for the first time the chemical content of the volatile fractions (VFs) along with the antifungal and anti-biofilm of L.

Botanical and Genetic Identification Followed by Investigation of Chemical Composition and Biological Activities on the L. Stem from Tunisian Flora.

Scarce information about the phenolic composition of L. is available, and no carotenoid compounds have been reported thus far. In this study the phenolic and carotenoid composition of this plant was both investigated and associated bioactivities were evaluated.

Identification of Fatty Acid, Lipid and Polyphenol Compounds from L. Kernel Extracts.

Apart from its essential oil, L. kernel extract has received only scarce attention. The present study aimed to describe the lipid and polyphenolic composition of the dichloromethane, chloroform, ethyl acetate, and ethanol extracts on the basis of hot extraction, performing analysis by gas chromatography and high-performance liquid chromatography coupled with mass spectrometry.

Natural Products among Brown Algae: The Case of Cystoseira schiffneri Hamel (Sargassaceae, Phaeophyceae).

A chemotaxonomic study on the marine brown alga Cystoseira schiffneri collected from the Tunisian marine coast allowed us to identify kjellmanianone (1) and a new isololiolide derivative named schiffnerilolide (2). The structure elucidation and the assignment of relative configurations of the isolated natural products were based on advanced mass spectrometric and nuclear magnetic resonance techniques. This outcome suggested a close phylogenetic relationship of C.

Evaluation of Antioxidant, Anticholinesterase, and Antidiabetic Potential of Dry Leaves and Stems in Tamarix aphylla Growing Wild in Tunisia.

Tamarix aphylla (L.) Karst. has a wide geographic distribution and was employed in traditional medicine as astringent, anti-rheumatic and to treat fever.

Green dyeing process of modified cotton fibres using natural dyes extracted from Tamarix aphylla (L.) Karst. leaves.

This research work involves an eco-friendly dyeing process of modified cotton with the aqueous extract of Tamarix aphylla leaves. During this process, the dyeing step was carried out on modified cotton by several cationising agents in order to improve its dyeability. The influence of the main dyeing conditions (dye bath pH, dyeing time, dyeing temperature, salt addition) on the performances of this dyeing process were studied.

Chemical composition, antioxidant and antimicrobial effects of Tunisian Limoniastrum guyonianum Durieu ex Boiss extracts.

In the present investigation, extracts obtained from L. guyonianum Durieu ex Boiss. aerial parts were used to evaluate total phenolic, flavonoid and tannin contents.

Essential Oil Constituents and Antioxidant Activity of Asplenium Ferns.

Two fern species Asplenium adiantum-nigrum L. and Asplenium trichomanes L. collected from the Kroumiria region (Northwest of Tunisia) were individually submitted to hydrodistillation in a Clevenger type apparatus.

Volatile Profile of Herniaria fontanesii Growing Spontaneously in Tunisia.

The essential oil extracted from Desfontaine's rupturewort, Herniaria fontanesii J. Gay subsp. fontanesii growing wildly in Tunisia, was analyzed using GC and GC-MS techniques.

Chemical composition and antioxidant activity of essential oil from aerial parts of Teucrium flavum L. subsp. flavum growing spontaneously in Tunisia.

The objectives of this study were to chemically characterise and evaluate the antioxidant potential of the essential oil from Teucrium flavum L. subsp. flavum growing spontaneously in Tunisia.

Synthesis and analgesic activity of alkylated, reduced and constrained oligoheterocyclic peptidomimetic analogs of Leu-enkephalin.

We report the design and the parallel solid phase synthesis of linear and oligoheterocyclic peptidomimetic analogs of Leu-enkephalin. The described peptidomimetics represent different unique scaffolds that distribute in the space the peptidyl side chains of amino acids essential for biological activity and mimic the bioactive conformation of the Leu-enkephalin peptide. All the compounds were screened in competitive radioligand binding assays to determine their affinities for μ-(MOR), and κ-(KOR) opioid receptors.

Metabolite profiling of polyphenols in the Tunisian plant Tamarix aphylla (L.) Karst.

In this study, a detailed investigation on the composition of polyphenols of Tamarix aphylla (L.) Karst., consisting of phenolic acids and flavonoids, was carried out.

Comparative study on the chemical constituents of essential oils from different organs of the Sicilian Kundmannia (Kundmannia sicula L.) DC. (Apiaceae) growing spontaneously in Tunisia.

Essential oils from odorous and volatile compounds possessing several therapeutic benefits are considered of a paramount importance in everyday human life. This study deals with a comparative study of essential oils from different parts of an aromatic plant Kundmannia sicula (L.) DC.

The Effect of Vitis vinifera L. Leaves Extract on Leishmania infantum.

Vitis vinifera L.is a traditional Asian herb widely used for different health problems. In the present research, the ethanolic and the aqueous extracts of Vitis vinifera L.

A novel methylated sesquiterpene from seagrass Posidonia oceanica (L.) Delile.

Phytochemical investigation of chloroform extract from the leaves of the marine plant Posidonia oceanica (L.) Delile (Posidoniaceae), yielded posidozinol, a new methylated sesquiterpene along with β-sitosterol and four known fatty acids: palmitic, palmitoleic, oleic and linoleic acids. The structure elucidation has been established on the basis of 1D- and 2D-NMR spectroscopy, GS/MS and ES mass spectrometry.

Antibacterial, antifungal and cytotoxic activities of two flavonoids from Retama raetam flowers.

We have investigated the antibacterial, antifungal and cytotoxic activities of two flavonoids isolated from Retama raetam flowers using the disc diffusion and micro-dilution broth methods. The cytotoxic activity was tested against Hep-2 cells using the MTT assay. The compounds licoflavone C (1) and derrone (2) were active against Pseudomonas aeruginosa and Escherichia coli (7.

Chemical composition and in vitro evaluation of antioxidant and antibacterial activities of the root oil of Ridolfia segetum (L.) Moris from Tunisia.

The present work describes the chemical composition and evaluates the antibacterial and the antioxidant properties of root oil from Ridolfia segetum, a traditional medicinal plant widely distributed in Tunisia. The essential oil, analysed by combination of GC, GC/MS and (13)C-NMR, was dominated by dillapiole (47.4%) and myristicin (19.

Two new sesquiterpene derivatives from the Tunisian endemic Ferula tunetana Pom.

A new sesquiterpene ester, tunetanin A (1), a new sesquiterpene coumarin, tunetacoumarin A (2), together with eight known compounds, i.e., coladin (3), coladonin (4), isosmarcandin (5), 13-hydroxyfeselol (6), umbelliprenin (7) propiophenone (8), beta-sitosterol (9), and stigmasterol (10), were isolated from the roots of Ferula tunetana.

Flower and root oils of the tunisian Daucus carota L. ssp. maritimus (Apiaceae): integrated analyses by GC, GC/MS, and 13C-NMR spectroscopy, and in vitro antibacterial activity.

The essential oils from flowers and roots of Daucus carota L. ssp. maritimus were obtained by hydrodistillation and analyzed by combination of GC, GC/MS, and (13)C-NMR.

Spasmolytic and anti-inflammatory effects of constituents from Hertia cheirifolia.

A sesquiterpenoid Bakkenolide (1), and two steroids, (3beta, 22E)-Stigmasta-5, 22-diène-3-ol (Stigmasterol) (2) and stigmasterol 3beta-glucoside (3), isolated from the Hertia cheirifolia (L.) chloroform extract, were evaluated respectively for their spasmolytic and anti-inflammatory activities. We note that these natural products were isolated and purified for the first time from the specie Hertia cheirifolia.

Purification of a natural insecticidal substance from Cestrum parqui (Solanaceae).

Cestrum parqui is a shrub originating from Chile used in Tunisia as an ornamental plant. The toxicity of this plant was observed for the first time on the Desert Locust Schistocerca gregaria. It was shown that the toxicity of the plant is concentrated in the Crude Saponic Extract (CSE).

Mutagenic, antimutagenic and antioxidant activities of a new polyphenolic and a flavonoid substances isolated from Anagallis monelli.

A new polyphenolic natural substance: 2,5-dihydroxy-benzoic acid 3'-formyl-5'-hydroxy-phenyl ester (1), Anamighrinal and 3-(O-alpha-L-rhamnosyl) quercetin (2) have been isolated from the methanolic aerial part extract of the plant Anagallis monelli by chromatographic separation. Their structures have been deduced essentially by one and two NMR spectroscopic procedures and mass spectrometry. Antioxidant, mutagenic, antimutagenic activities, of the natural products were realised and positive results were recorded.

A new C9 nor-isoprenoid glucoside from Rantherium suaveolens.

The new C(9) nor-isoprenoid 3-methyl-octa-1,5-diene-7-one-3-O-beta-D-glucopyranoside, named as ranthenone glucoside (1), together with the previously known 9-hydoxylinaloyl glucoside (2), sitosterol-3beta-O-[6'-palmitoyl-beta-D-glucopyranoside] (3), scopoletin (4), fraxetin (5), and scopolin (6), were isolated from the aerial parts of Rantherium suaveolens. The structures of these compounds were elucidated by extensive spectroscopic analysis.

Essential oil composition of terminal branches, cones and roots of Tetraclinis articulata from Tunisia.

The volatiles obtained separately from the terminal branches (woody and non-woody), cones and roots of Tetraclinis articulata gathered from the area of Zaghouan (Tunisia) have been analyzed by GC and GC-MS. Remarkable differences were found between the constituent percentages of the different studied organs. The main components in the non-woody branches volatile oil were naphtalen (6.

Chemical composition and antifungal activity of volatiles from three Opuntia species growing in Tunisia.

The chemical composition of the volatiles isolated by steam distillation from leaves, flowers and fruits of Opuntia lindheimeri var. linguiformis L. Benson, leaves and flowers of Opuntia macrorhiza Engelm and leaves of Opuntia microdasys (Lehmann) gathered in the sea cliff of Monastir town (Tunisia), has been studied by GC and GC-MS.