Publications by authors named "Zinajda Zolic-Karlsson"

Multiple sclerosis (MS) patients experience long-term deterioration of neurological function, reduced quality of life, long-lasting treatment cycles, and an increased risk of early workability loss imposing an economic burden to society. Autologous haematopoietic stem cell transplantation (AHSCT) has shown promising treatment effects for relapsing remitting MS (RRMS). This study employs a micro-costing approach to estimate healthcare utilization and costs associated with AHSCT in Norwegian RRMS patients.

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Objectives: To describe healthcare utilization and estimate associated costs during 1 year of follow-up among older people seeking primary care due to a new episode back pain and to describe healthcare utilization across patients with different risk profiles stratified using the StarT Back Screening Tool (SBST).

Design: Prospective cohort study.

Participants And Setting: A total of 452 people aged ≥55 years seeking Norwegian primary care with a new episode of back pain were included.

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Article Synopsis
  • - The study investigates modifiable prognostic factors linked to high healthcare costs among older adults (55+) with new back pain episodes, considering data from two cohort studies.
  • - Four key factors were identified as significantly associated with high healthcare costs: higher pain severity, disability, depression, and poorer physical health quality of life, while kinesiophobia and recovery expectations showed no significant link.
  • - The findings suggest these factors could be targets for future interventions aimed at reducing healthcare utilization and costs for older adults suffering from back pain.
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This study estimated the cost-effectiveness of liver transplantation in patients with colorectal liver metastases confined to the liver with progressive disease, compared with alternative treatment options: TAS-102, regorafenib, or best supportive care. Using a mathematical simulation model, people’s life expectancy and healthcare costs over 25 years were estimated. Transplanted patients lived for 4.

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Aims: The purpose was to compare operative treatment with a volar plate and nonoperative treatment of displaced distal radius fractures in patients aged 65 years and over in a cost-effectiveness analysis.

Methods: A cost-utility analysis was performed alongside a randomized controlled trial. A total of 50 patients were randomized to each group.

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Article Synopsis
  • * The study involved 180 patients who received either antibiotics or a placebo, measuring outcomes in terms of quality-adjusted life years (QALYs) over 12 months and analyzing healthcare costs.
  • * Results showed that the antibiotic group had higher healthcare costs and a cost per QALY gained of €24,625, with a 51% probability of being cost-effective within a willingness-to-pay threshold of €27,500.
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