Occurrence, Transport, and Full-Scale Adsorptive Removal of PFAS in Electroplating Parks in China.

The electroplating industry is an important source of per- and polyfluoroalkyl substances (PFAS) contamination, but there is a lack of comprehensive studies on the occurrence, transport, and removal of PFAS in electroplating parks. In this study, we investigated typical electroplating parks in China and conducted the first full-scale removal of PFAS from chromium-plating wastewater using pore-enlarged granular activated carbon (GAC) and hydrophobic anion exchange resin (AER). The results showed that 6:2 fluorotelomer sulfonate (6:2 FTS) gradually replaced perfluorooctanesulfonate (PFOS) in China's electroplating industry.

Polysaccharides from Lactarius volemus Fr. ameliorate high-fat and high-fructose diet induced metabolic disorders and intestinal barrier dysfunction.

Our research was conducted to investigate the effects of Lactarius volemus Fr. polysaccharides (LVP) on metabolic disorders and intestinal barrier dysfunction in HFFD-induced obese mice. Our findings demonstrated that LVP supplementation significantly ameliorated hyperlipoidemia and hyperglycemia, insulin resistance and hepatic inflammation.

Optimized single-bath dyeing of bio-based nylon 56/cotton blends with vat dyes: Mechanistic insights and process enhancements.

Nylon 56/cotton (N/C) blended fabrics have excellent durability and can cater to various clothing needs. However, the quality and value of textile garments are significantly influenced by the dyeing process. Due to variations in the structure and characteristics of nylon 56 and cotton fibers in blended fabrics, achieving consistent coloration is challenging, resulting in noticeable color discrepancies.

The microglial innate immune receptor TREM2 participates in fear memory formation through excessive prelimbic cortical synaptic pruning.

Introduction: Fear memory formation has been implicated in fear- and stress-related psychiatric disorders, including post-traumatic stress disorder (PTSD) and phobias. Synapse deficiency and microglial activation are common among patients with PTSD, and induced in animal models of fear conditioning. Increasing studies now focus on explaining the specific mechanisms between microglia and synapse deficiency.

Sleep quality and emotional eating in college students: a moderated mediation model of depression and physical activity levels.

Background: Emotional eating is a prevalent maladaptive coping mechanism among college students, which is associated with mental health and sleep concerns. Though previous studies have established a link between sleep quality, depression and emotional eating, most of these have been in Western populations. In addition, few existing studies have taken physical activities into account, and the underlying mechanisms between these four variables remain to be further studied.

Flexible Crossbar Molecular Devices with Patterned EGaIn Top Electrodes for Integrated All-Molecule-Circuit Implementation.

Here, a unique crossbar architecture is designed and fabricated, incorporating vertically integrated self-assembled monolayers in electronic devices. This architecture is used to showcase 100 individual vertical molecular junctions on a single chip with a high yield of working junctions and high device uniformity. The study introduces a transfer approach for patterned liquid-metal eutectic alloy of gallium and indium top electrodes, enabling the creation of fully flexible molecular devices with electrical functionalities.

Dynamically blocking leakage current in molecular tunneling junctions.

Molecular tunneling junctions based on self-assembled monolayers (SAMs) have demonstrated rectifying characteristics at the nanoscale that can hardly be achieved using traditional approaches. However, defects in SAMs result in high leakage when applying bias. The poor performance of molecular diodes compared to silicon or thin-film devices limits their further development.

Fabrication of multi-functional molecular tunnelling junctions by click chemistry.

Continuous advancement in molecular electronics demands increasing functionality and diversity of integrated molecular junctions; however, single-functional molecular junctions fail to meet these requirements. In this article, we propose the use of a widely applicable and efficient click reaction on the surface to modify self-assembled monolayers (SAMs) to achieve multifunctional molecular tunnelling junctions, current rectification and memristance, on a single chip. This approach has allowed us to meet the growing demand for versatility and functionality in molecular electronic devices.

Single-cell landscape analysis reveals systematic senescence in mammalian Down syndrome.

Background: Down syndrome (DS), which is characterized by various malfunctions, is the most common chromosomal disorder. As the DS population continues to grow and most of those with DS live beyond puberty, early-onset health problems have become apparent. However, the cellular landscape and molecular alterations have not been thoroughly studied.

OBOX regulates mouse zygotic genome activation and early development.

Zygotic genome activation (ZGA) activates the quiescent genome to enable the maternal-to-zygotic transition. However, the identity of transcription factors that underlie mammalian ZGA in vivo remains elusive. Here we show that OBOX, a PRD-like homeobox domain transcription factor family (OBOX1-OBOX8), are key regulators of mouse ZGA.

A Study on the Fatigue Performance and Corrosion Resistance of 304/45 Bimetallic Composite Bolts.

This paper utilized a hot-rolling process to produce composite rods and subsequently manufactured 304/45 composite bolts through the process of drawing and thread rolling. The study focused on examining the microstructure, fatigue performance, and corrosion resistance of these composite bolts. Additionally, the impacts of quenching and tempering on the fatigue performance of the composite bolts were explored and compared to the performance of 304 stainless steel (SS) bolts and Grade 6.

A composite energy harvester based on human reciprocating motion.

In this paper, a piezoelectric electromagnetic composite energy harvester is studied. The device consists of a mechanical spring, upper and lower base, magnet coil, etc. The upper and lower bases are connected by struts and mechanical springs and secured by end caps.

The Age of Mobility: Can Equalization of Public Health Services Alleviate the Poverty of Migrant Workers?

Migrants workers are important participants in and contributors to economic and social construction, but they still face the reality of being marginalized. Based on data from the China Migrants Dynamic Survey in 2018, this paper systematically investigated the impact of public health services on the multidimensional poverty of migrant workers. The research found that, first, the current mean of the multidimensional poverty deprivation value of migrant workers is 0.

Correction: Plasmon enhanced light-matter interaction of rice-like nanorods by a cube-plate nanocavity.

[This corrects the article DOI: 10.1039/D1NA00777G.].

Plasmon enhanced light-matter interaction of rice-like nanorods by a cube-plate nanocavity.

Plasmonic nanocavity is widely used for enhancing light-matter interaction. Here, an efficient plasmonic nanocavity of the cube-plate system is constructed for the fluorescence enhancement of rice-like CdSe/CdS nanorods (NRs) with tunable emission wavelength. Over ten thousand times fluorescence enhancement is achieved with the assistance of the plasmonic nanocavity.

Two new lactam derivatives from a derived fungus PQJ-2.

A new bicyclic lactam derivatives penicilactam B () and a new monocyclic amide penicillamide D (), along with four known compounds (), were isolated from the fermentation broth of the derived fungus PQJ-2. Their structures and stereochemistry were elucidated by comprehensive spectroscopic analyses and quantum ECD calculations. All the compounds were evaluated for their antibacterial activities against subsp and insecticidal activity against Hubner.

Construction of a cross-species cell landscape at single-cell level.

Individual cells are basic units of life. Despite extensive efforts to characterize the cellular heterogeneity of different organisms, cross-species comparisons of landscape dynamics have not been achieved. Here, we applied single-cell RNA sequencing (scRNA-seq) to map organism-level cell landscapes at multiple life stages for mice, zebrafish and Drosophila.

Microglia-derived TNF-α inhibiting GABAergic neurons in the anterior lateral bed nucleus of the stria terminalis precipitates visceral hypersensitivity induced by colorectal distension in rats.

Irritable bowel syndrome (IBS) is a common and debilitating gastrointestinal disorder that is exacerbated by stress and characterized by abdominal pain. Although microglia in the CNS have been implicated as an important mediator of the stress response, the role of microglia and microglia-GABAergic neuron interactions in the limbic area, most notably BNST, in the development of colorectal hypersensitivity has not been determined. We established a neonatal colorectal distension-induced chronic visceral hyperalgesia model in rats.

Parametric analysis of the output performance of a valveless piezoelectric pump with a bullhorn-shaped structure.

In response to the serious problem of backflow in valveless piezoelectric pumps, this paper proposes a valveless piezoelectric pump with a bullhorn-shaped structure. In this paper, we analyze the flow guide by using the "tail flow space pressure comparison method" and "fluid unit dynamic analysis method," revealing the working principle of the flow guide in the valveless piezoelectric pump. The effects of the height, sharp angle, and filter angle of the bullhorn-shaped structure on the output flow were investigated separately by the experiment.

Causal Inference Machine Learning Leads Original Experimental Discovery in CdSe/CdS Core/Shell Nanoparticles.

The synthesis of CdSe/CdS core/shell nanoparticles was revisited with the help of a causal inference machine learning framework. The tadpole morphology with 1-2 tails was experimentally discovered. The causal inference model revealed the causality between the oleic acid (OA), octadecylphosphonic acid (ODPA) ligands, and the detailed tail shape of the tadpole morphology.

Construction of a human cell landscape at single-cell level.

Single-cell analysis is a valuable tool for dissecting cellular heterogeneity in complex systems. However, a comprehensive single-cell atlas has not been achieved for humans. Here we use single-cell mRNA sequencing to determine the cell-type composition of all major human organs and construct a scheme for the human cell landscape (HCL).

The role of SOCS3 in the hypothalamic paraventricular nucleus in rat model of inflammatory pain.

Background: Inflammatory molecular signals are modulated by a variety of intracellular transduction pathways, the activation of which may induce and amplify the spread of inflammatory response. Suppresser of cytokine signaling 3 (SOCS3) is an established negative feedback regulation transcription factor associated with tumor, diabetes mellitus, inflammation and anaphylaxis. Herein, we investigated whether SOCS3 in the paraventricular nucleus (PVN) can attenuate pro-inflammatory responses, and thereby relieve the inflammatory pain.