Publications by Zimeng Yin

Publications by authors named "Zimeng Yin"

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AZD1775 and anti-PD-1 antibody synergistically sensitize hepatoma to radiotherapy.

Yichun Yin Jian Wang Junxuan Yi Kaiyue Zhang Zimeng Yin

Chin Med J (Engl)

January 2024

Background: Radiation (IR)-induced DNA damage triggers cell cycle arrest and has a suppressive effect on the tumor microenvironment (TME). Wee1, a cell cycle regulator, can eliminate G2/M arrest by phosphorylating cyclin-dependent kinase 1 (CDK1). Meanwhile, programed death-1/programed death ligand-1 (PD-1/PDL-1) blockade is closely related to TME.

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