Publications by authors named "Zimeng Gao"
Article Synopsis
- - The study investigates the factors that affect survival outcomes in patients with pTNM staging after mastectomy, aiming to create a prediction model and identify which patients benefit from postmastectomy radiotherapy (PMRT).
- - Researchers analyzed data from 936 patients, revealing that those who received PMRT had significantly better overall survival (OS) and disease-free survival (DFS) after surgery, especially in high-risk groups, while low and intermediate-risk groups did not show the same benefits.
- - Key high-risk factors identified included age under 40, tumor location, lymph node involvement, and a specific Ki-67 level, highlighting that certain patients (with a risk score ≥149) who received PMRT experienced notable improvements in
Vibrio alginolyticus is one of the most common opportunistic pathogens in marine animals and humans. In this study, A transposon mutation library of the V. alginolyticus E110 was used to identify motility-related genes, and we found three flagellar and one capsular polysaccharide (CPS) synthesis-related genes were linked to swarming motility.
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- - Non-immune hydrops fetalis (NIHF) can have various genetic causes that can be identified using exome sequencing (ES), which enhances traditional prenatal diagnostic methods.
- - A systematic review of 31 studies involving 445 NIHF cases found a 37% diagnostic rate, indicating that ES is particularly effective in consanguineous cases compared to non-consanguineous ones.
- - The genetic variants identified included several disease categories, primarily RASopathies (24%) and neuromuscular disorders (21%), with a majority of cases showing recessive inheritance patterns (55%).
We aim to determine the spectrum of cytogenetic abnormalities and outcomes in unbalanced offspring of asymptomatic constitutional balanced t(9;22) carriers through a systematic literature review. We also include a case of a constitutional balanced t(9;22) carrier from our institution. Among the 16 balanced t(9;22) carriers in our review, 13 were maternal and 3 were paternal.
View Article and Find Full Text PDFType 1 von Willebrand disease (VWD) is the most common subtype of VWD, comprising 75% of VWD patients. We provide a systematic review of type 1 VWD in pregnancy. Our objective was to evaluate the rate of postpartum hemorrhage (PPH) in patients with known type 1 VWD.
View Article and Find Full Text PDFUltrasound methods in conjunction with microbubbles have been used for brain drug delivery, treatment of stroke, and imaging of cerebral blood flow. Despite advances in these areas, questions remain regarding the range of ultrasound parameters that disrupt the blood-brain barrier (BBB). In this study, several conditions were investigated to either enhance or reduce the likelihood of BBB disruption.
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