Publications by authors named "Zilvinas Chomanskis"

Article Synopsis
  • The study investigates the effects of electrical stimulation of the caudal ventrolateral medulla (CVLM) on blood pressure and survival in Wistar rats, suggesting a potential target for treating primary arterial hypertension (PAH).
  • Twenty rats were divided into experimental and control groups, with significant decreases in arterial pressure and heart rate observed in the experimental group during the OFF stimulation phase, indicating the CVLM's role in blood pressure regulation.
  • Though there are risks associated with stimulating medullary neural centers, this research highlights CVLM as a promising target for future deep brain stimulation therapies for drug-resistant hypertension, necessitating potential advancements in electrode technology for clinical use.
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The control circuits of blood pressure have a strong neural regulatory element important in the pathogenesis of essential drug-resistant hypertension. Targeting lower medullary neural control mechanisms of blood pressure by electrical stimulation could be beneficial, and therefore, a novel device is needed. This paper presents a remotely programmable deep brain stimulator with an invasive continuous blood pressure monitoring system in a non-tethered rat model.

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Background: Plexiform neurofibromas are extremely rarely found in the region of cauda equina and can pose a significant challenge in the diagnostic and management sense. To our knowledge, only 7 cases of cauda equina neurofibromatosis (CENF) have been reported up-to-date.

Case Summary: We describe a case of a 55-year-old man with a 10 years history of progressive lower extremities weakness and bladder dysfunction.

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The association between traumatic brain injury and brain cancer is a matter of debate. The available literature is sparse and yields conflicting results. Even though there is a pathophysiological rationale for post-traumatic intracranial cancerogenesis, the direct link still has not been proven.

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