Background: Microvascular invasion (MVI) is a significant indicator of the aggressive behavior of hepatocellular carcinoma (HCC). Expanding the surgical resection margin and performing anatomical liver resection may improve outcomes in patients with MVI. However, no reliable preoperative method currently exists to predict MVI status or to identify patients at high-risk group (M2).
View Article and Find Full Text PDFDue to the information non-independence of attributes, combined with a complex and changeable environment, the analysis of risks faces great difficulties. In view of this problem, this paper proposes a new three-way decision-making (3WD) method, combined with prospect theory and a non-additive measure, to cope with multi-source and incomplete risk information systems. Prospect theory improves the loss function of the original 3WD model, and the combination of non-additive measurement and probability measurement provides a new perspective to understand the meaning of decision-making, which could measure the relative degree by considering expert knowledge and objective data.
View Article and Find Full Text PDFBackground: The prognosis for hepatocellular carcinoma (HCC) in the presence of cirrhosis is unfavourable, primarily attributable to the high incidence of recurrence.
Aim: To develop a machine learning model for predicting early recurrence (ER) of post-hepatectomy HCC in patients with cirrhosis and to stratify patients' overall survival (OS) based on the predicted risk of recurrence.
Methods: In this retrospective study, 214 HCC patients with cirrhosis who underwent curative hepatectomy were examined.
The direct utilization of low-light images hinders downstream visual tasks. Traditional low-light image enhancement (LLIE) methods, such as Retinex-based networks, require image pairs. A spiking-coding methodology called intensity-to-latency has been used to gradually acquire the structural characteristics of an image.
View Article and Find Full Text PDFAclacinomycin A (ACM-A) is an anthracycline antitumor agent widely used in clinical practice. The current industrial production of ACM-A relies primarily on chemical synthesis and microbial fermentation. However, chemical synthesis involves multiple reactions which give rise to high production costs and environmental pollution.
View Article and Find Full Text PDFInt J Environ Res Public Health
January 2023
Enrofloxacin is an important antimicrobial drug that is widely used in aquaculture. Enrofloxacin residues can have negative effects on aquatic environments and animals. The toxicological effects of different concentrations of enrofloxacin residues in cultured water on Chinese mitten crabs () were compared.
View Article and Find Full Text PDFAccumulating evidence suggests that traditional Chinese medicine (TCM) has significant effects on reducing 24-h urinary protein (24-h UPRO) and improves renal function indices. The current level of evidence-based medicine is still not enough due to the limitation of clinical center size and sample size. We aimed to update the current evidence on the efficacy of TCM in the treatment of diabetic kidney disease (DKD).
View Article and Find Full Text PDFSilica-fume-polyvinyl-alcohol-fiber-reinforced concrete (SPRC) is a green and environmentally friendly composite material incorporating silica fume and polyvinyl alcohol fiber into concrete. To study the impact resistance of SPRC, compressive-strength and drop hammer impact tests were conducted on SPRC with different silica-fume and polyvinyl-alcohol-fiber contents. The mechanical and impact resistance properties of the SPRC were comprehensively analyzed in terms of the compressive strength, ductility ratio and impact-energy-dissipation variation.
View Article and Find Full Text PDFBackground: This study aimed to detect the effect of angiotensin receptor 1 (AT1) knock out (KO) on spermatogenesis and hypothalamic-pituitary-gonadal (HPG) axis hormone expression.
Methods: Normal C57BL/6 male mice were used as control group or treated with angiotensin receptor blocker, in addition heterozygous ± AT1KO mice were generated. After caged at a ratio of 2 to 1 with females, pregnancy rates of female mice were determined by detection of vaginal plugs.
Developing a porous separation membrane that can efficiently separate oil-water emulsions still represents a challenge. In this study, nanofiber membranes with polydopamine clusters polymerized and embedded on the surface were successfully constructed using a solution blow-spinning process. The hierarchical surface structure enhanced the selective wettability, superhydrophilicity in air (≈0°), and underwater oleophobicity (≈160.
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