Publications by authors named "Zilia Y Munoz-Ramirez"
Article Synopsis
- - The study investigates the genetic variants of a wild chili pepper ancestor, originating from regions in North and Central America, by analyzing genomic data from two samples: CHMX_Ch1 from Chihuahua and QO from Querétaro, Mexico.
- - A total of 226 million paired-end reads were generated for CHMX_Ch1, resulting in 210,324 detected variants, compared to 169,718 variants found in QO, including SNPs and InDels.
- - The research highlights significant genetic functions, revealing that variants in CHMX_Ch1 are primarily linked to gene regulation and metabolic processes, providing valuable insights for future studies on chiltepin pepper genetics.
Helicobacter pylori, a dominant member of the gastric microbiota, shares co-evolutionary history with humans. This has led to the development of genetically distinct H. pylori subpopulations associated with the geographic origin of the host and with differential gastric disease risk.
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- Horizontal gene transfer (HGT) enables the transfer of adaptive traits between bacterial species, potentially leading to rapid developments such as zoonotic disease transmission and antibiotic resistance.
- The physical separation of species in different ecological niches creates barriers to HGT, but when species cohabitate, such as in the same host, the rate of gene transfer increases significantly.
- Research on 30 bacterial species reveals that being in the same environment can boost HGT by six times, contributing to a significant portion of genetic variation and highlighting the role of ecological factors in bacterial evolution.
The gastric bacterium shares a coevolutionary history with humans that predates the out-of-Africa diaspora, and the geographical specificities of populations reflect multiple well-known human migrations. We extensively sampled from 16 ethnically diverse human populations across Siberia to help resolve whether ancient northern Eurasian populations persisted at high latitudes through the last glacial maximum and the relationships between present-day Siberians and Native Americans. A total of 556 strains were cultivated and genotyped by multilocus sequence typing, and 54 representative draft genomes were sequenced.
View Article and Find Full Text PDFIn the present study, we evaluated the ability of the Virtual Analysis Method for Phylogenomic fingerprint Estimation (VAMPhyRE) toolkit to classify human mitochondrial DNA (mtDNA) haplogroups. In total, 357 random mtDNA sequences were obtained from different haplogroups, based on the classification of PhyloTree. Additionally, we included a control group of five sequences (Pan paniscus, Pan troglodytes, Homo sapiens neanderthalensis, Yoruba15, and the revised Cambridge reference sequence).
View Article and Find Full Text PDFHelicobacter pylori is a common component of the human stomach microbiota, possibly dating back to the speciation of Homo sapiens. A history of pathogen evolution in allopatry has led to the development of genetically distinct H. pylori subpopulations, associated with different human populations, and more recent admixture among H.
View Article and Find Full Text PDF(HP) genetics may determine its clinical outcomes. Despite high prevalence of HP infection in Latin America (LA), there have been no phylogenetic studies in the region. We aimed to understand the structure of HP populations in LA mestizo individuals, where gastric cancer incidence remains high.
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