Publications by authors named "Zilei Xu"

Article Synopsis
  • - The study investigates the differences in dorsal penile nerve somatosensory evoked potentials (DNSEP) among three groups: patients with acquired premature ejaculation (APE), primary premature ejaculation (PPE), and healthy controls, aiming to better understand the condition and its underlying mechanisms.
  • - Results indicate that while there were no significant differences in the P40 latency among groups, PPE patients had higher DNSEP amplitudes at one measurement site, while APE patients had lower amplitudes; both PE groups exhibited shorter P30 latencies compared to controls.
  • - The study suggests that segmental DNSEP could help identify neurological issues related to premature ejaculation, informing future clinical approaches, although it acknowledges limitations such as the innovative P30/P40 ratio and
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Background: The pathogenesis of primary premature ejaculation (PPE) is complex, and the pathologic basis may be an overactive sympathetic nervous system.

Aim: To investigate sertraline efficacy in patients with sympathetic hyperexcitability in PPE and clarify the value of penile sympathetic skin response (PSSR) in assessing the efficacy of sertraline for PPE treatment.

Methods: Sixty-three patients with PPE were recruited in the outpatient clinic and asked to take 50 mg of oral sertraline daily for a 4-week treatment period.

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Optical voltage imaging in neurons is a popular technology in the study of neural electrophysiology, which has been applied in many disciplines, including neurological, gastrointestinal and cardio-cerebrovascular sciences and mental health. However, few reports are seen on its application in the study of neurogenic ED. This article presents an overview of neuronal optical voltage imaging in the study of neurological ED, including its development, classification, technical theories and the possibility of its application in neurological ED research, hoping to provide some new ideas for researchers in the related fields.

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Background: Uretero-arterial fistula (UAF) is a disease that usually involves the aorta, common iliac artery, external iliac artery, hypogastric artery, and lumbar artery. Among them, uretero-lumbar artery fistula (ULAF) is the most unusual type. So, both in China and around the world, the diagnosis and treatment of ULAF is a big challenge.

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