A lysosome-targeted fluorescent probe with large Stokes shift for visualizing biothiols and .

Lysosomal biothiols play critical roles in numerous cellular processes and diseases. Researching an effective method for real-time labeling biothiols in lysosomes is of great significance and urgency, as it could provide essential information for the diagnosis of relevant diseases. In this study, we developed a lysosome-targeted fluorescent probe (LY-DCM-P) with a large Stokes shift of 150 nm for the sensitive and selective detection of biothiols and .

The translation and validation of the Organ Transplant Symptom and Well-Being Instrument in China.

To translate the Organ Transplant Symptom and Well-Being instrument (OTSWI) into Chinese and test the reliability and validity of the Chinese version. A total of 259 patients with organ transplants were recruited from The First Affiliated Hospital of China Medical University in Shenyang, from November 2020 to January 2021. Construct validity was evaluated using exploratory factor analysis (EFA) and reliability were assessed using test-retest reliability and internal consistency.

Factors influencing employment rates and states after liver transplantation in China: A multi-centre cross-sectional study.

Aim: The aim of this study was to assess employment rates and states and the factors influencing liver transplant recipients in China.

Design: A cross-sectional study.

Methods: A total of 212 liver transplant recipients were included in this study.

Mediating Role of Hope Between Social Support and Self-Management Among Chinese Liver Transplant Recipients: A Multi-Center Cross-Sectional Study.

This study aimed to investigate the common status of self-management in liver transplant recipients and to explore the mediating role of hope in the relationship between social support and self-management. Two hundred and ten liver transplant recipients from two tertiary hospitals were included. Questionnaires were used for general demographic information, the Perceived Social Support Scale, the Herth Hope Index, and the Self-Management Questionnaire for Liver Transplantation Recipients.

Mediating effect of coping style on the relationship between clinical leadership and quality of work life among nurses in tertiary-level hospitals in China: a cross-sectional study.

Objective: To explore the association between clinical leadership and quality of work life, as well as the mediating role of coping style in this relationship.

Setting: Three tertiary-level hospitals in Liaoning Province, China.

Participants: A total of 1209 nurses were recruited for this study.