Merkel cell carcinoma (MCC) is an aggressive neuroendocrine carcinoma with a high rate of metastasis and mortality. We present 68 Ga-DOTATATE PET/CT and 68 Ga-pentixiafor PET/CT findings of MCC in a 62-year-old man. Both 68 Ga-DOTATATE PET/CT and 68 Ga-pentixiafor PET/CT revealed increased radioactive uptake of lesions in the scan range.
View Article and Find Full Text PDFObjective: To perform a meta-analysis of the efficacy and safety about Lu-DOTATATE therapy for advanced/metastatic pNETs based on the current clinical evidence.
Methods: This systematic review follows the PRISMA guideline. Search PubMed, Medline, EMBASE and CNKI, VIP, Wanfang databases, from establishment to June 2022, on the study of Lu-DOTATATE for advanced/metastatic pNETs, the primary endpoint was to evaluate the treatment effect through DRRs and DCRs.
Purpose: Several studies have demonstrated that Ga-FAPI PET/CT shows high intratumoral tracer uptake and low normal tissue uptake, allowing for excellent visualization of cancer. The purpose of this study was to compare the ability of Ga-FAPI and F-FDG PET/CT for the evaluation of newly diagnosed NSCLC.
Materials And Methods: A prospective analysis of 28 individuals with histopathologically newly confirmed NSCLC that underwent Ga-FAPI and F-FDG PET/CT was conducted.
Dermatofibrosarcoma protuberans is a rare soft tissue sarcoma with a high recurrence rate. Herein, we present 68Ga-FAPI and 18F-FDG PET/CT findings of dermatofibrosarcoma protuberans in a 45-year-old man. Dermatofibrosarcoma protuberans only shows limited FDG uptakes on 18F-FDG PET/CT, but demonstrated intense tracer uptakes on 68Ga-FAPI PET/CT.
View Article and Find Full Text PDFPurpose: The present retrospective analysis sought to compare the relative diagnostic efficacy of [Ga]Ga-DOTA-FAPI-04 to that of [F]FDG PET/CT as a means of detecting bone metastases in patients with a range of cancer types.
Materials: In total, 30 patients with bone metastases associated with different underlying malignancies were retrospectively enrolled. All patients had undergone [Ga]Ga-DOTA-FAPI-04 and [F]FDG PET/CT, and the McNemar test was used to compare the relative diagnostic performance of these two imaging modalities.
A 46-year-old man presented with a 3-month history of epistaxis. CT and MRI scan showed a soft tissue mass in the left nasal cavity. An excisional biopsy of the mass revealed extramedullary plasmacytoma.
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