Publications by authors named "Ziju Wang"
Article Synopsis
- Alström syndrome (ALMS) is a rare genetic disorder caused by mutations in the ALMS1 gene, characterized by symptoms such as retinal dystrophy, obesity, hearing loss, and type 2 diabetes.
- A 10-year-old Chinese girl with ALMS was studied, revealing novel genetic variants through advanced sequencing methods, including a frameshift mutation and a large deletion in the ALMS1 gene.
- The study concluded that these new genetic findings enhance the understanding of ALMS1 mutations and provide valuable clinical insights into the syndrome, especially in patients with unique structural anomalies like cor triatriatum sinister (CTS).
Background: Apathy is among the most prevalent and incapacitating non-motor symptoms of Parkinson's disease (PD). PD patients with apathy (PD-A) have been reported to have abnormal spontaneous brain activity mainly in 0.01-0.
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- Spectral computed tomography shows promise for better imaging and reducing artifacts using an energy resolution method for x-rays.
- A new approach utilizing a fully connected neural network (FCNN) has been developed to correct errors from x-ray crosstalk in edge-on detectors.
- Experimental results indicate that this method enhances image quality by minimizing crosstalk effects and increasing the accuracy of energy resolution in the reconstructed images.