High sediment load weakens the effects of nitrogen nutrients on zooplankton diversity in a continental-scale river.

Suspended sediment is a major factor driving biodiversity in sediment-laden rivers. However, the composition of aquatic communities and their diversity responses to sediment-nutrient interactions in large-scale sediment-laden rivers are largely unexplored. This study investigated the distribution patterns of zooplankton communities in the main stream of the Yellow River, China.

Bias-Induced Ga-O-Ir Interface Breaks the Limits of Adsorption-Energy Scaling Relationships for High-Performing Proton Exchange Membrane Electrolyzers.

Rationally manipulating the in situ formed catalytically active surface of catalysts remains a significant challenge for achieving highly efficient water electrolysis. Herein, we present a bias-induced activation strategy to modulate in situ Ga leaching and trigger the dynamic surface restructuring of lamellar Ir@GaO for the electrochemical oxygen evolution reaction. The in situ reconstructed Ga-O-Ir interface sustains high water oxidation rates at oxygen evolution reaction (OER) overpotentials.

Biological volume EM with focused Ga ion beam depends on formation of radiation-resistant Ga-rich layer at block face.

Volume electron microscopy (vEM) enables biologists to visualize nanoscale 3D ultrastructure of entire eukaryotic cells and tissues prepared by heavy atom staining and plastic embedding. The highest resolution vEM technique is focused ion-beam scanning electron microscopy (FIB-SEM), which provides nearly isotropic (~5-10 nm) spatial resolution at fluences of > 10,000 e/nm. However, it is not clear how such high resolution is achievable because serial block-face (SBF) SEM, which incorporates an in-situ ultramicrotome instead of a Ga FIB beam, results in radiation-induced collapse of similar specimen blocks at fluences of only ~20 e/nm.

HIV risk and influence factors among MSM who had sought sexual partners in core venues: a continuous sentinel surveillance in 2010-2022.

Background: Seeking sexual partners in men who have sex with men (MSM) venues has been regarded as a high-risk behavior for HIV among MSM. Nevertheless, with the implementation of venue-based interventions and the change in the way MSM seek sexual partners, the continued status of MSM venues as the HIV risk factor remains inconclusive. This study endeavors to delve into this ambiguity by examining the MSM sexual contact network (SCN) as a foundation.

Self-healing actuatable electroluminescent fibres.

Alternating-current electroluminescent fibres are promising candidates as light sources for smart textiles and soft machines. However, physical damage from daily use causes device deterioration or failure, making self-healable electroluminescent fibres attractive. In addition, soft robots could benefit from light-emitting combined with magnetically actuated functions.

Densely Populated Cell and Organelles Segmentation with U-Net Ensembles.

The complex and highly intertwined morphology of activated platelets within thrombi poses significant challenges for segmentation. In this work, we present a robust dual-network pipeline for cell and organelle segmentation. This multi-network approach enables the detection of fine details near the membrane while simultaneously facilitating long-range smoothing in regions distal to the membrane, drastically improving the performance of the watershed clustering algorithm compared to single-network approaches.

Comprehensive Investigation of Homology and Heterogeneity Between Aurantii Fructus and Aurantii Fructus Immaturus Using Chemometrics Combined with Network Pharmacology.

Aurantii Fructus (AF) and Aurantii Fructus Immaturus (AFI) are distinct herbs outlined by the Chinese Pharmacopoeia. They are sourced from the same plant but harvested at different times, resulting in differences in efficacy. It is important to avoid mixing them clinically and to distinguish between the two.

The protective effect of erythropoietin and its novel derived peptides in peripheral nerve injury.

Peripheral nerve injury seriously endangers human life and health, but there is no clinical drug for the treatment of peripheral nerve injury, so it is imperative to develop drugs to promote the repair of peripheral nerve injury. Erythropoietin (EPO) not only has the traditional role of promoting erythropoiesis, but also has a tissue-protective effect. Over the past few decades, researchers have confirmed that EPO has neuroprotective effects.

A low-latency graph computer to identify metastable particles at the Large Hadron Collider for real-time analysis of potential dark matter signatures.

Image recognition is a pervasive task in many information-processing environments. We present a solution to a difficult pattern recognition problem that lies at the heart of experimental particle physics. Future experiments with very high-intensity beams will produce a spray of thousands of particles in each beam-target or beam-beam collision.

The FGFR2 Variant rs13387042 is Associated With Breast Cancer Risk: A Meta-Analysis and Systematic Review.

Objective: The association of FGFR2-rs13387042 polymorphism with breast cancer (BC) susceptibility in women remains inconclusive due to varying reports. In this study, we conducted a meta-analysis to explore the relationship between FGFR2-rs13387042 polymorphism and susceptibility to BC.

Methods: Relevant literature were acquired through searches across multiple databases.

Exosomal circ_0000722 derived from periodontal ligament stem cells undergoing osteogenic differentiation promotes osteoclastogenesis.

Periodontal ligament stem cells (PDLSCs), which are considered promising stem cells for regeneration of periodontal bony tissue, can also manipulate alveolar bone remodeling by exosomes. In this study, we investigated interactions between PDLSCs under osteogenic differentiation and osteoclast precursors. The results showed that conditioned medium from PDLSCs under 5d osteogenic induction promoted osteoclastogenesis of RAW264.

Panax japonicus C.A. Meyer: a comprehensive review on botany, phytochemistry, pharmacology, pharmacokinetics and authentication.

Background: Panax japonicus C.A. Meyer (Zhujieshen) is widely used in traditional medicine as a tonic hemostatic and anti-inflammatory agent in China, Japan, and Korea.

Serum metabolomics analysis of biomarkers and metabolic pathways in patients with colorectal cancer associated with spleen-deficiency and qi-stagnation syndrome or damp-heat syndrome: a prospective cohort study.

Objective: To profile the serum metabolites and metabolic pathways in colorectal cancer (CRC) patients associated with spleen-deficiency and qi-stagnation syndrome (SDQSS) or damp-heat syndrome (DHS).

Methods: From May 2020 to January 2021, CRC patients diagnosed with traditional Chinese medicine (TCM) syndromes of SDQSS or DHS were enrolled. The clinicopathological data of the SDQSS and DHS groups were compared.

Species Differentiation and Quality Evaluation for Atractylodes Medicinal Plants by GC/MS Coupled with Chemometric Analysis.

The utilization of rhizomes from the genus Atractylodes has been challenging due to their closely related origins. In this study, we developed an analytical strategy to differentiate Atractylodes lancea (A. lancea), Atractylodes chinensis (A.

Prognostic relevance of rib invasion and modification of T description for resected NSCLC patients: A propensity score matching analysis of the SEER database.

Introduction: The impact of rib invasion on the non-small cell lung cancer (NSCLC) T classifications remains unclear. Our study aims to verify the impact of rib invasion on survival in patients with NSCLC through multicenter data from the Surveillance, Epidemiology, and End Results (SEER) database, and proposed a more appropriate pT for the forthcoming 9 tumor-node-metastasis (TNM) classifications.

Method: The SEER database was used to collect TNM NSCLC cases from the period of 2010-2015 according to the 7 TNM classification system.

Associations between plasma metal levels and mild renal impairment in the general population of Southern China.

Background: Metal exposure were assumed to be closely related with declined renal function, but the conclusions were controversial. We employed diverse statistical models and assessed the association between metal mixture exposure and mild renal impairment.

Methods: A total of 13 plasma metals were measured in 896 general population from Southern China.

Self-Assembly 3D Porous Crumpled MXene Spheres as Efficient Gas and Pressure Sensing Material for Transient All-MXene Sensors.

Environmentally friendly degradable sensors with both hazardous gases and pressure efficient sensing capabilities are highly desired for various promising applications, including environmental pollution monitoring/prevention, wisdom medical, wearable smart devices, and artificial intelligence. However, the transient gas and pressure sensors based on only identical sensing material that concurrently meets the above detection needs have not been reported. Here, we present transient all-MXene NO and pressure sensors employing three-dimensional porous crumpled MXene spheres prepared by ultrasonic spray pyrolysis technology as the sensing layer, accompanied with water-soluble polyvinyl alcohol substrates embedded with patterned MXene electrodes.

Variations in airborne pollen and spores in urban Guangzhou and their relationships with meteorological variables.

Airborne pollen causes various types of allergies in humans, and the extent of allergic infection is related to the presence of different types of sporo-pollen and existing meteorological conditions in a certain area. Therefore, an aeropalynological study of 72 airborne samples with a hydrofluoric acid (HF) treatment was conducted in the Haizhu district of Guangzhou, China, in 2016, to identify the temporal variations in airborne sporo-pollen and the relationship between airborne sporo-pollen concentrations and different meteorological variables in Guangzhou, China. Forty-five types of airborne pollen, seven types of airborne spores, and some undetermined sporo-pollen taxa were identified with two separate plant habitats occurring during this period (from January to December 2016): arboreal pollen (tree-based) and non-arboreal pollen (herb, shrub, aquatic, liane, etc.

Scaling Metal-Elastomer Composites toward Stretchable Multi-Helical Conductive Paths for Robust Responsive Wearable Health Devices.

Stretchable electronics have advanced rapidly and many applications require high repeatability and robustness under various mechanical deformations. It has been described here that how a highly stretchable and reliable conductor composite made from helical copper wires and a soft elastomer, named eHelix, can provide mechanically robust and strain-insensitive electronic conductivity for wearable devices. The reversibility of the mechanical behavior of the metal-elastomer system has been studied using finite element modeling methods.